肺炎婴儿危重病例评分与血小板数量关系探讨

Investigation into the relationship between the platelet count and the severity of pneumonia in infants

目的探讨血小板数量与婴儿肺炎严重程度的关系。方法福建医科大学附属三明第一医院儿科2011-11/2013-02收治166例肺炎患儿,根据入院24h内小儿危重病例评分法分为非危重组76例、危重组69例和极危重组21例,3组均在入院后24h内采集末梢血测定血小板,对3组患儿末梢血血小板数量和人数分布进行对比。结果末梢血血小板数量危重组（427.1±73.6）×10~9/L高于非危重组（343.3±61.2）×10~9/L,差异有统计学意义（P〈0.05）,显著高于极危重组（102.1±29.5）×10~9/L,差异有统计学意义（P〈0.01）;极危重组低于危重组和非危重组,差异有统计学意义（P〈0.01）;危重组血小板增高（〉300×10~9/L）占82.6%（57/69）,极危重组血小板降低（〈100×10~9/L）占66.7%（14/21）。结论肺炎患儿危重组血小板数明显升高,极危重组血小板数明显降低,密切监测血小板的变化对判断病情和估计预后有一定帮助。

Objective To investigate the relationship between the platelet count and the severity of pneumonia in infants.Methods From Nov.2011 to Feb.2013,166 cases of infants with pneumonia were divided into three groups（non critical group,critical group and extremely critical group）according to the score of critical illness in children in 24 hafter admission.Peripheral blood platelets were collected in 24 hafter admission.The number of peripheral blood platelets in three groups was compared.Results The peripheral blood platelets[（427.1±73.6）×109/L]was higher in critical group than in non-critical group[（343.3±61.2）×109/L]（P〈0.05）,and was significantly higher than extremely critical group[（102.1±29.5）×109/L]（P〈0.01）;both differences had statistical significance.Conclusion The number of peripheral blood platelets in the critical group is significantly increased,and the number of peripheral blood platelets in the extremely critical group was significantly decreased.Close monitoring of the changes of peripheral blood platelet is helpful in judging the severity of illness and the prognosis of disease.