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抗感染药物导致的急性肾损伤 被引量:1

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摘要 目的探讨抗感染药物引发急性肾损伤(AKI)的临床特点及治疗情况。方法选取50例药物引起AKI的患者为研究对象,回顾其用药种类、肾损伤特点、治疗情况。结果抗感染药物种类中氨基糖苷类占46%、糖肽类占10%、β-内酰胺类占30%,其他占14%。经积极治疗,92%症状消失,8%仍需血液透析维持治疗,无死亡病例,平均随访6个月,病情稳定88%。结论临床抗感染药物引发的AKI率较高,与多种致病因素共同作用相关,多发生在有基础合并症的老年患者及病情较重的高危患者中,氨基糖苷类、糖肽类、β-内酰胺类为目前常见肾毒性药,需重视合理用药,加强高危人群防范,重视AKI预防和监控,以降低其发生风险,最大程度改善疾病预后。
作者 季泽俊
出处 《中国实用医药》 2015年第34期176-177,共2页 China Practical Medicine
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