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VEGF在鼻咽癌组织中的表达研究

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摘要 目的探讨血清血管内皮细胞生长因子(VEGF)水平与鼻咽癌发生及淋巴结转移的关系。方法运用酶联免疫吸附测定法定量检测50例鼻咽癌患者(鼻咽癌组)、40例鼻咽部良性疾病患者(良性疾病组)和35例健康者(健康组)血清中的VEGF含量。并比较检测结果。结果鼻咽癌组患者血清中的VEGF表达水平[(425.43±239.56)ng/L]与良性疾病组[(140.36±108.67)ng/L]、健康组[(113.98±38.49)ng/L]比较,差异均有统计学意义(P<0.05);有淋巴结转移患者血清中的VEGF表达水平明显增高,差异有统计学意义(P<0.05)。结论血清VEGF水平检测可用于鼻咽癌的早期诊断,与鼻咽癌淋巴结转移相关。
作者 马庆 付娟
出处 《中国实用医药》 2015年第32期33-34,共2页 China Practical Medicine
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