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达英-35联合克罗米芬不同间隔启动促排卵治疗多囊卵巢综合征的临床研究 被引量:1

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摘要 目的探讨多囊卵巢综合征(PCOS)患者应用炔雌醇环丙孕酮片(达英-35)联合枸橼酸氯米芬胶囊(克罗米芬)不同间隔促排卵对妊娠的影响。方法 42例PCOS不孕患者,均给予达英-35治疗,患者均在3周期内分泌调整正常,随后启动克罗米芬(CC)促排卵。根据促排卵前停用达英-35的时间不同分为短间隔组(20例)和长间隔组(22例)。短间隔组口服达英-35治疗3个周期后,从撤退性出血第5天开始加用CC;长间隔组口服达英-35治疗3个周期,停药至少1个月经周期,从撤退性出血第5天开始加用CC。比较两组排卵率、妊娠率。结果短间隔组排卵率(72.2%)与长间隔组排卵率(73.7%)比较差异无统计学意义(P>0.05);短间隔组妊娠率为22.2%显著高于长间隔组的52.6%(P<0.05)。结论 PCOS不孕患者给予达英-35治疗后停用至少1个月经周期后,再CC启动促排卵,可显著提高其临床妊娠率。
作者 次仁 郝汇平
出处 《中国实用医药》 2015年第32期136-138,共3页 China Practical Medicine
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参考文献4

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