成都地区中老年人群LDLC升高的流行状况及影响因素

Study on Prevalence of High LDLC and Risk Factors in Middle-aged and Elderly Population in Chengdu Area

目的探讨成都城乡地区中老年人群LDLC升高的流行状况及影响因素,为今后本地区脂代谢异常防治奠定基础。方法样本的获取采用分层整群抽样的方法,以社区（村）为单位,抽取城乡社区40~79岁有代表性人群5 230人进行LDLC及相关因素的调查。结果成都地区中老年人群LDLC升高的患病率2.18%。标化患病率为2.03%。40~74岁人群随年龄增大LDLC升高的患病率逐渐增高;75岁以后患病率略有下降。男女两性及城乡患病率差异均无显著性（P均〉0.05）。成都地区中老年男性人群LDLC升高的危险因素为年龄、糖尿病,适度饮酒为保护因素;中老年女性人群LDLC升高的危险因素为分娩巨大儿、腹型肥胖、糖尿病,保护因素为适度饮酒、体力锻炼。结论成都地区中老年人群LDLC升高的患病率较低,明显低于全国水平。成都乃至四川地区冠心病的相对低发可能与人群高LDLC血症的低患病率有关。防治糖尿病、适度饮酒、合理体力锻炼对预防LDLC升高可能有积极意义。

Aim To investigate the present prevalence and risk factors of high LDLC among middle and aged population in urban and rural areas of Chengdu,and to lay the foundation for the future of hyperlipidemia prevention.Methods To investigate the prevalence of high LDLC and influential factors in Chengdu. 5230 persons of 40 ~ 79 years old in the urban and rural communities were investigated. Data were collected through questionnaire,physical examination,and laboratory tests. Results The prevalence rate of elevated LDLC among middle-aged and elderly people was2. 18% in Chengdu and the standardized prevalence rate was 2. 03%. In 40 ~ 74 years old,the prevalence of elevated LDLC increased gradually with age. The prevalence rate decreased slightly after 75 years old. There was no difference in the prevalence of urban and rural areas. The risk factors of high LDLC in middle-aged and elderly male population in Chengdu area were age and diabetes. Moderate drinking was a protective factor. Risk factors of elevated LDLC in middle-aged and elderly women were rmacrosomia,abdominal obesity and diabetes,protective factors were moderate alcohol consumption and physical exercise. Conclusion Prevalence of elevated LDLC among middle-aged and elderly people in urban and rural Chengdu is low. It is lower than the national level. To decrease prevalence of high low density lipoprotein cholesterol is of great significance for the prevention and treatment of coronary heart disease. Prevention of diabetes,moderate drinking and physical exercise may have positive significance in the prevention of elevated LDLC.