亚胺培南药物利用评价标准的建立及应用

Establishment and Application of the Drug Use Evaluation Criteria on Imipenem

目的:为临床合理使用亚胺培南提供参考。方法:参考DUE标准建立方法,采用文献研究和专家咨询法,建立亚胺培南药物利用评价(DUE)标准。设计调查表,收集我院使用的亚胺培南使用病例资料,评估该药物使用情况。结果:建立的亚胺培南DUE标准包括用药指征、用药过程、治疗结果三部分。我院亚胺培南在用药过程部分的肝/肾功能监测、联合用药、给药疗程及药品不良反应监测等方面存在不合理现象。结论:建立的亚胺培南DUE标准实用性好,可为临床药师开展工作提供参考。

OBJECTIVE：To provide basis for the reasonable use of imipenem.METHODS：Referring to the methods to establish DUE criteria,by literature study and expert consultation,DUE criteria was established and questionnaire was designed to collect the data of imipenem use,in order to evaluate the use of imipenem.RESULTS：Established DUE criteria contained medication indications,medication process and treatment results.Unreasonable use of imipenem in our hospital was found in fields of liver/renal function test,drug use,treatment course and ADR monitoring.CONCLUSIONS：The established DUE criteria of imipenem shows strong practicability,and provide reference for the work development of clinical pharmacists.