COPD合并TB患者血清IgM、IgG、IgA含量的临床分析

Clinical Analysis of COPD and TB Patient Serum IgM, IgG, IgA Content

目的研究慢性阻塞性肺疾病(COPD)合并肺结核(TB)时血清中免疫球蛋白Ig M、Ig G、Ig A含量变化。方法选取在我院就诊的慢性阻塞性肺疾病(COPD)合并肺结核(TB)的患者(试验组),以及单纯慢性阻塞性肺疾病(COPD)和单纯肺结核(TB)还有正常健康人(健康对照组)的体液免疫功能进行对比分析。观察Ig M、Ig G、Ig A含量。结果四组间比较,Ig M均无统计学意义,Ig A:试验组高于COPD组、试验组高于健康对照组、TB组高于COPD组、TB组高于健康对照组、差异有高度统计学意义。Ig G:试验组高于COPD组,TB组高于COPD组,差异有高度统计学意义。结论当COPD合并TB患者Ig G和Ig A水平均明显升高,这种情况可能对COPD合并TB患者是一种保护作用。

Objective To investigate the changes of IgM, IgG, IgA in patients who with lung tuberculosis complicated by chronic obstructive pulmonary disease（COPD）. Methods Select COPD complicated with TB named observation group, patients with COPD, patients with TB and health people, investigate the changes of IgM, IgG, IgA. Results Comparison between the four groups, IgM had no statistical significance. IgA Observation group batter than the COPD group, observation group batter than the health group, TB group batter than the health group. IgG observation group batter than the COPD group, TB group batter than the COPD group. Conclusion When lung tuberculosis complicated by chronic obstructive pulmonary disease IgG and IgA were elevated, This may be a protective effect in patients.