期刊文献+

吗啡治疗晚期肿瘤患者呼吸困难的临床观察 被引量:5

下载PDF
导出
摘要 目的观察吗啡缓解晚期肿瘤患者呼吸困难的有效性和安全性。方法将80例经病理证实的晚期肿瘤患者随机分成观察组和对照组各40例,对照组患者均常规吸氧,并使用支气管扩张药及糖皮质激素。观察组除与观察组相同治疗并加用盐酸吗啡片10 mg Q12h。次日比较两组患者治疗后呼吸困难改善情况和不良反应。结果观察组治疗有效率优于对照组,差异有统计学意义(P<0.05)。两组不良反应主要为呼吸抑制、恶心、呕吐及便秘,差异无统计学意义(P>0.05)。结论盐酸吗啡片能有效治疗晚期肿瘤患者呼吸困难,不良反应轻,值得临床推广。
出处 《中国医药指南》 2016年第2期174-175,共2页 Guide of China Medicine
  • 相关文献

参考文献7

  • 1郝希山,魏于全,赫捷.肿瘤学[M].北京:人民卫生出版社,2015:373-375.
  • 2Ben-Aharon I,Gafter-Gvili A,Leibovici L,et al.Interventions for alleviating cancer-related dyspnea:a systematic review and metaanalysis[J].Acta Oncol,2012,51(8):996-1008.
  • 3Cheung WY,Zimmermann C.Pharmacologic management of cancerrelated pain,dyspnea,and nausea[J].Semin Oncol,2011,38(3):450-459.
  • 4刘峰,王美玲,袁海花,王彦,姜斌.吗啡、甲强龙及氨茶碱治疗晚期肿瘤患者呼吸困难疗效比较[J].上海交通大学学报(医学版),2013,33(6):823-826. 被引量:5
  • 5Bonnichon A,Le Floch H,Riviere F,et al.Dyspnea in lung cancer[J].Rev Pneumol Clin,2008,64(2):62-68.
  • 6Parshall MB,Schwar tzstein R M,Adams L,et al.A n off icial American Thoracic Society statement:update on the mechanis ms,assessment,and management of dyspnea[J].Am J Respir Crit Care Med,2012,185(4):435-452.
  • 7白娟,郑玲,伍建蓉,谷焰.皮下注射吗啡缓解晚期肿瘤顽固呼吸困难的临床研究[J].西部医学,2012,24(9):1709-1710. 被引量:4

二级参考文献28

  • 1李金祥 RbertG Twycross MellarP Davis.姑息医学[M].北京:人民卫生出版社,2005,4..
  • 2American Thoracic Society. Dyspnoea mechanisms, assessment and management a consensus statement[J]. Am J Respir Crit Care Med, 1999, 159:321-340.
  • 3Coghill RC, Sang SN, Maisog JM, et al. Pain intensity process- ing with in the human brain: a bilateral distributed mechanism [J]. J Neurol Physio, 1999, 82:1934-1943.
  • 4Paiffer C, Poline JB, Thivard L, et al. Neural substrates for the perception of acutely induced dyspnoea [J]. Am J Rsepir Care Med, 2001, 163:951-957.
  • 5Jennings AL, Davies AN, Higgins JPT, et al. Opioids for the palliation of breathlessness in terminal illness [J]. Cochrane Da- tabase Syst Rev, 2004, 57 (1):939-941.
  • 6Jennings AL, Davies AN, Higgins JPT, etal. A systematic re- view o[ the use of opioids in the management of dyspnoea[J]. Thorax, 2002, 57; 939-944.
  • 7Polosa R, Simidchiev A, Waiters EH. Nebulised morphine for severe interstitial lung disease [J]. Cochrane Database Syst Rev, 2004, 50(8) : 759-763.
  • 8Pool PJ, Veale AG, Black PN. The effect of sustained-release morphine on breathlessness and quality of life in severe chronic obstructive pulmonary disease[J]. Am J Respir Crit Care Med, 1998, 157: 1877-1880.
  • 9Varkey, Basil MD. Palliative care for end-stage lung disease patients [J]. Clin Pul Med, 2003, 10(5), 269-277.
  • 10Cohen MH, Anderson AJ, Krasnow SH, et al. Continuous in- travenous infusion of morphine for severe dyspnea [J]. South MedJ, 1991, 84: 229-234.

共引文献7

同被引文献44

引证文献5

二级引证文献23

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部