摘要
基于生物质资源的平台化学品制造,是解决目前石化资源枯竭和环境问题的重要措施,对经济社会的可持续发展具有重要意义。本文主要介绍了系统生物学和合成生物学在有机酸(琥珀酸、富马酸、L-苹果酸、葡萄糖二酸、丙酮酸、苯丙酮酸、α-酮戊二酸)以及其他平台化学品(2,5-呋喃二甲酸)生物制造中的应用,并展望了生物制造在平台化学品生产中的未来发展方向。
Due to the limited amount of fossil fuels and global warming problem, bio-manufacturing based on renewable biomass has been paid more attention. In this review, the contribution of systems biology and synthetic biology in bio-manufacture of platform chemicals like organic acid such as succinate, fumarate, malate, glucaric acid, pyruvate, phenylpyruvic acid, α-ketoglutarate and other platform chemicals such as 2,5-furandicarboxylic acid are reviewed. Finally, the trends of bio-manufacture for platform chemical are prospected.
出处
《化工学报》
EI
CAS
CSCD
北大核心
2016年第1期129-139,共11页
CIESC Journal
基金
国家重点基础研究发展计划项目(2012CB720802
2013CB733602)
国家自然科学基金项目(21390204)~~
