长链非编码RNA在神经系统疾病中的研究进展

Research progress on long non-coding RNA in nervous system diseases

神经系统疾病的病因复杂,严重影响人类的健康。近年来,长链非编码RNA(lncRNAs)已成为神经系统的研究热点。lncRNAs广泛参与人类神经系统疾病的病理生理进程。本文主要讨论lncRNAs在神经系统疾病中的研究进展,重点阐述lncRNAs在神经退行性疾病、神经胶质瘤、中风和精神分裂症中的研究进展。

The etiologies of neurological diseases are complex,which seriously affect human health. Recently, long non-coding RNAs（ lncRNAs） have become a hot research topic in the nervous system.Many research results show that lncRNAs are involved in the pathophysiological processes of human neurological diseases. In this review,we discuss the research progress on lncRNAs in neurological diseases and mainly illustrate the research progress of lncRNAs in neurodegenerative disease,gliomas,stroke and schizophrenia.