2010—2013年国内外实体器官移植研究文献数据分析

Analysis of research hotspot concerning publications on organ transplantation

目的分析目前实体器官移植研究文献数据，为我国实体器官移植领域临床和科研工作者把握重点研究方向提供信息支持。方法利用文献计量学方法，对2010至2013年中国科学引文数据库（CSCD）和WebofScience数据库中实体器官移植研究的前100篇（Top100）中文和英文文献进行归纳分析，采用共词分析法对高频主题词进行分析，以文章的发表年份、国家和机构分布、来源期刊、栏目类型、研究内容等为统计指标，总结实体器官移植学科研究热点的内在特征。结果Top100中、英文文献中出现频次前10位的关键词／主题词分布提示，中文高被引文献主要涉及免疫抑制剂、器官捐献、术后并发症和排斥反应等方面；英文高被引文献主要涉及外科手术技术、受者存活情况、排斥反应和免疫移植等方面。Top100中、英文高被引文献分别来自50和58家机构，集中于知名医疗机构和高等院校；排名前10的机构分别有高被引论文47和43篇，论文总被引频次分别占总量的45．5％和47．4％。Top100中、英文高被引文献分别分布于27和36种期刊中，发文量排名前10的期刊分别发表75和70篇，总被引分别为316和7694次。结论通过分析文献数据，可为相关研究人员把握研究方向提供参考依据。

Objective To analyze the current research focus of solid organ transplantation in order to provide information for Chinese clinicians and researchers for research direction and topic selection. Method By using bibliometric method, the Chinese Science Citation Database and Web of Science were thoroughly searched and highly cited papers concerning solid organ transplantation were summarized and analyzed from 2010 to 2013. With the year of publication, national and institutional distribution, source journals, column type, research content as indicators, all the keywords of high- frequency were analyzed via co-word analysis method in order to summarize the characteristics of hot research subject in the field of solid organ transplantation. Result From 2010 to 2013, topl00 highly cited articles in Chinese had a preference for liver transplantation, followed by kidney transplantation, immunosuppressant, organ donation, postoperative complication and rejection, while articles in English mainly focused on surgical technique, recipient survival, transplant immunity and rejection. Top 100 highly cited articles were from 50 and 58 institutions for Chinese and English, respectively. There were 47 papers from top 10 institutions in Chinese, accounting for 45.6% of the total citations. There were 43 papers from top 10 institutions in English, accounting for 47. 4% of the total citations. Top 100 highly cited papers in Chinese were distributed in 27 journals. The top 10 journals published 75 papers, which have been cited for 316 times. Top 100 highly cited papers in English were distributed in 36 journals. The top 10 journals published 70 papers, which have been cited for 7 694 times. Conclusion Domestic experts and scholars should pay continuous attention to the organ donation issues related to research in the future, with reference to the advanced experience of Europe and the United States and other countries. Solid organ transplantation registry, data center report and update, transplant recipient prognosis and long-term survival should be highly focused.