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巨噬细胞对间充质干细胞成骨分化影响的研究进展 被引量：3

Advancement of the effect of macrophage on mesenchymal stem cells in osteogenesis
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摘要 间充质干细胞（mesenchymal stem cells,MSC）由于来源广泛,且具有自我增殖和多向分化潜能等特点,在再生医学和组织工程方面具有广阔的应用前景。目前,关于MSC成骨分化的研究很多,但对MSC定向成骨分化的相关机制依旧不甚清楚,导致体内、外成骨效率仍然较低。如何提高MSC的成骨性能已成为关注的热点。
作者 易志新 邹学农 彭建强
机构地区 广东医学院附属深圳福田人民医院脊柱外科 中山大学附属第一医院脊柱外科
出处 《中国脊柱脊髓杂志》 CAS CSCD 北大核心 2015年第12期1116-1119,共4页 Chinese Journal of Spine and Spinal Cord
关键词 成骨分化 间充质干细胞 巨噬细胞 成骨效率 组织工程 骨髓来源 再生医学 细胞结构 脂肪来源 微环境
分类号 Q254 [生物学—细胞生物学]
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二级参考文献179

  • 1Pittenger MF;Mackay AM;Beck SC.Multilineage potential of adult human mesenchymal stem cells,1999.
  • 2Zuk PA.Human adipose tissue is a source of multipotent stem cells,2002.
  • 3Friedenstein AJ;Shapiro-Piatetzky II;Petrakova KV.Osteogenesis in transplants of bone marrow cells,1966.
  • 4Urist MR.Bone: Formation by AutoinductionScience,1965.
  • 5Liu J,Wang H,Zuo Y,Farmer SR.Functional interaction between peroxisome proliferator-activated receptor gamma and beta-catenin. Molecular and Cellular Biology . 2006
  • 6Caplan AI.Why are MSCs therapeutic? New data: new insight. Journal of Paleopathology . 2009
  • 7Gronthos S,Mankani M,Brahim J,et al.Postnatal human dental pulp stem cells (DPSCs) in vitro and in vivo. Proceedings of the National Academy of Sciences of the United States of America . 2000
  • 8Horwitz EM,Gordon PL,Koo WK,et al.Isolated allogeneic bone marrow-derived mesenchymal cells engraft and stimulate growth in children with osteogenesis imperfecta: implications for cell therapy of bone. Proceedings of the National Academy of Sciences of the United States of America . 2002
  • 9Horwitz EM,Prockop DJ,Fitzpatrick LA,et al.Transplantability and therapeutic effects of bone marrow-derived mesenchymal cells in children with osteogenesis imperfecta. Nature Medicine . 1999
  • 10Mareschi K,Biasin E,Piacibello W,et al.Isolation of human mesenchymal stem cells: bone marrow verses umbilical cord blood. Haematologica . 2001

共引文献50

同被引文献26

  • 1孙强,邱勇,刘臻,陈军浩,王斌,俞杨,陈蕾蕾,马薇薇.Runx2在青少年特发性脊柱侧凸患者骨髓间质干细胞中的表达及意义[J].中国脊柱脊髓杂志,2005,15(10):616-619. 被引量：3
  • 2Pirraco RP, Reis RL, Marques AP. Effect of monocytes/macrophages on the early osteogenic differentiation of hBMSCs. ] Tissue Eng Regen Med, 2013, 7(5): 392-400.
  • 3Chen C, Uluda~ H, Wang Z, et al. Macrophages inhibit migration, metabolic activity and osteogenic differentiation of human mesenchymal stem ce/ls in vitro. Cells Tissues Organs, 2012, 195(6): 473-483.
  • 4Guihard P, Danger Y, Brounais B, et al. Induction of osteogenesis in mesenchymal stem cells by activated monocytes/macrophages depends on oncostatin M signaling. Stem Cells, 2012, 30(4): 762-772.
  • 5Ekstr6m K, Omar O, Gran41i C, et al. Monocyte exosomes stimulate the osteogenic gene expression of mesenchymal stem cells. PLoS One, 2013, 8(9): e75227.
  • 6Sims NA, Gooi JH. Bone remodeling: Multiple cellular interactions required for coupling of bone formation and resorption. Semin Cell Dev Biol, 2008, 19(5): 444-451.
  • 7Fridovich I. The biology of oxygen radicals. Science, 1978, 201(4359): 875-880.
  • 8Poyton RO, Ball KA, CasteUo PR. Mitochondrial generation of free radicals and hypoxic signaling. Trends Endocrinol Metab, 2009, 20(7): 332-340.
  • 9Jabs T. Reactive oxygen intermediates as mediators of programmed cell death in plants and animals. Biochem Pharrnacol, 1999, 57(3): 231-245.
  • 10McCubrey JA, Lahair MM, Franklin RA. Reactive oxygen species- induced activation of the MAP kinase signaling pathways. Antioxid Redox Signal, 2006, 8(9-10): 1775-1789.

引证文献3

二级引证文献12

中国脊柱脊髓杂志
2015年 第12期

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