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抗体免疫诱导治疗在肝移植中的应用 被引量：5

Application of immune induction therapy with antibodies in liver transplantation
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摘要 抗体免疫诱导治疗在肝移植中的应用越来越普遍。论述了目前常见免疫诱导抗体及其在肝移植中的应用情况,指出了抗体免疫诱导治疗减少激素及钙调磷酸酶抑制剂(CNI)(如环孢素和他克莫司)用量,从而有效降低感染发生、保护肾功能以及阻止急性排斥反应,最终改善移植受者的预后。关于抗体免疫诱导治疗对肝炎和肝癌的影响,仍需进一步探索。 Immune induction therapy with antibodies has been widely applied in liver transplantation. This paper introduces common antibodies for immune induction and their application in liver transplantation,and points out that immune induction therapy with antibodies reduces the dosage of hormones and calcineurin inhibitors（ cyclosporine and tacrolimus）,reduces infections effectively,protects renal function,prevents acute rejection reaction,and finally improves the prognosis of transplant recipients. The effect of immune induction therapy with antibodies on hepatitis and liver cancer still needs further investigation. Key words： liver transplantation; immunity induction; therapy
作者 杨扬 邓宜南
机构地区 中山大学附属第三医院肝脏移植中心
出处 《临床肝胆病杂志》 CAS 2015年第12期2031-2034,共4页 Journal of Clinical Hepatology
基金 国家自然科学基金(81300365、81370575、81570593) 广东省自然科学基金研究团队项目(2015A030312013)
关键词 肝移植 免疫诱导 治疗 liver transplantation immunity induction therapy
分类号 R657.3 [医药卫生—外科学]
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参考文献23

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二级参考文献15

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临床肝胆病杂志
2015年 第12期

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