摘要
目的:探讨Philips Achieva 3.0T TX磁共振直肠弥散峰度成像的可重复性。方法:应用Philips Achieva 3.0T TX超导型磁共振扫描仪。8通道体部相控阵线圈。对27例健康志愿者在不同时间(24小时~2周内)行两次行DKI扫描。DKI采用单次激发自旋回波-平面回波(SE-EPI)序列,启用5个扩散梯度场(b=0、500、1000、1500、2000 s/mm2),扩散梯度同时取X、Y和Z三个方向。由两名5年以上工作经验的医生双盲对图像进行后处理,获得同一层面的MD值、MK值,然后进行统计学分析。结果:所有27例志愿者均成功获得DKI数据。MD值及MK值观察者内相关系数分别为0.962、0.958;变异系数分别为17.8%、18.9%。MD值及MK值观察者间相关系数分别为0.925、0.895;变异系数分别为18.5%、23.6%。结论:直肠弥散峰度成像具有较高的可重复性。
Purpose: To assess the reproducibility of diffusion kurtosis imaging(DKI) for rectum. Methods: This study was approved by our institutional review board and with informed consent. Twenty-seven healthy volunteers underwent 3-T magnetic resonance imaging twice with an interval of 24 hours to 14 days by using axial fat suppressed single-shot echo-planar DK imaging (five b-values) and torso phased-array coil. Parameters maps were obtained for the metric K, a measure of excess kurtosis of diffusion, and corrected diffusion (D), a corrected diffusion coefficient accounting for the non-Gaussian behavior. The inter- and intra-observer consistency was evaluated by using reliability test in SPSS 11.5. Results: Paired t-tests demonstrated that there was no significant difference between inter- and intra-observer (all P〉0.05). Intra-class correlation coefficients of the inter- and intra-observer were 0.962 (D), 0.958 (K) and 0.925 (D), 0.895 (K) respectively. Coefficients of variation were 17.8% (D), 18.9% (K) and 18.5% (D), 23.6% (K). Conclusion: DKI showed good reproducibility between paired observers and paired scans. The parameters D and K would be the foundation for further experiments and clinical application of DK imaging.
出处
《中国医学计算机成像杂志》
CSCD
北大核心
2015年第6期524-527,共4页
Chinese Computed Medical Imaging
基金
福建省卫生计生委青年科研课题NO.2015-1-13~~
关键词
DKI
直肠
结果可重复性
水成像
Diffusional kurtosis imaging
Rectum
Reproducibility of results
Water diffusion