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中性粒细胞计数及中性粒细胞/淋巴细胞比值对ST段抬高型心肌梗死患者住院死亡和并发症的预测价值

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摘要 目的中性粒细胞增多是ST段抬高型心肌梗死(STEMI)后的一个重要特征,而该现象对STEMI患者临床预后的价值尚未确定。需要检测STEMI患者血液中细胞炎症反应与住院病死率及不良临床事件间的关系。方法选择2012年5月—2014年5月就诊于我院的368例STEMI患者,评估总白细胞数、细胞亚群数及中性粒细胞与淋巴细胞的比值(NLR)。通过多变量Logistic回归分析细胞炎症反应与心肌梗死后病死率及并发症的相关性。结果高龄(P=0.002),低射血分数(P=0.0008)以及中性粒细胞计数(P=0.03)均为死亡的预测因子。白细胞(P=0.02)和中性粒细胞计数增高(P=0.02)以及高NLR(P=0.01)为心力衰竭的预测因子。多变量分析显示中性粒细胞计数是死亡的独立预测因子(OR=2.9,1.1~8.2,P=0.03),而中性粒细胞计数[OR=1.14,CI(1.01~1.2),P=0.02],糖尿病[OR=2.54,CI(1.21~5.2),P=0.003]是心力衰竭的独立预测因子。结论血常规可以帮助评估STEMI患者死亡及心力衰竭风险,中性粒细胞计数是预测两者最有价值的指标。
作者 袁晖
机构地区 太原市晋机医院
出处 《基层医学论坛》 2015年第36期5056-5059,共4页 The Medical Forum
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