高同型半胱氨酸血症与青年脑梗死的相关性研究

The study of ralation between hyperhomocysteinemia with youth cerebral infarction

目的：探讨血浆同型半胱氨酸（Hcy）水平与青年脑梗死的关系。方法选取120例18岁～45岁的脑梗死患者为病例组，80例非脑血管病患者为对照组，比较2组的Hcy水平；将病例组按Hcy水平分为2组，比较2组之间的基本特征。结果病例组的Hcy水平高于正常对照组（P〈.05），且男性Hcy水平明显高于女性（P〈0.05）；病例组的组内比较，较高Hcy组的原发性高血压比例明显高于Hcy正常组（P〈0.05）。结论高同型半胱氨酸血症（Hhcy）可能是青年脑梗死的独立危险因素，对伴有高血压的青年男性应常规筛查Hcy，对防治青年脑梗死有重要意义。

ObjectiveTo investigate the ralation of plasma homocysteine（Hcy）level with youth cerebral infarction.Methods120 cases of cerebral infarction patients with 18-45 years of age as the case group,80 patients with non-vascular disease patients in the control group.According to the Hcy levels,patients were divided into two groups,basic features were compared.ResultsThe level of Hcy in the case group was higher than that in the normal control group （P〈0.05）,and the level of Hcy in male was significantly higher than that in female（P〈0.05）.In the case group,the proportion of primary hypertension in the high Hcy group was significantly higher than that in the normal Hcy group （P〈0.05）.Conclusionshyperhomocysteinemia（Hhcy）may be an independent risk factors of youth cerebral infarction, for young men with hypertension hcy can be routinely screened,it is important to prevention and treatment of youth cerebral infarction.