摘要
目的观察抗抑郁焦虑药物治疗功能性消化不良(functional dyspepsia,FD)的疗效。方法将符合标准的160例功能性消化不良患者随机分为2组,对照组80例为抗消化不良药物治疗组;治疗组80例为抗消化不良药物联合抗抑郁焦虑药物治疗组,通过8周治疗后,进行精神状态以及疗效评估。精神状态评估使用汉密尔顿抑郁量表(Hamilton depressionscale,HAMD)以及汉密尔顿焦虑量表(Hamilton anxiety scale,HAMA);疗效评估采用胃肠道症状评定量表(gastrointestinal symptom rating scale,GSRS)。结果治疗后2组患者HAMD评分、HAMA评分均较治疗前下降(P<0.05),治疗组较对照组改善更明显(P<0.05);治疗组的有效率为90%,明显高于对照组的63.75%(P<0.05)。结论功能性消化不良通过使用抗抑郁焦虑治疗可显著提高疗效。
ObjectiveTo observe the curative effect of antidepressant drugs and anti-anxietydrugs in the treatment of functional dyspepsia(functional dyspepsia,FD).MethodsUp to the standard of functional dyspepsia,160 cases of patients were randomly divided into two groups,control group 80 cases:use drugs for the treatment of indigestion;The treatment group 80 cases:with antidepressants drugs and anti-anxiety drugs,by 8 weeks after treatment,evaluate the two groups before and after treatment in spirit form evaluation andcurative effect evaluation.Spirit form evaluation using the Hamilton depression rating scale(Hamilton&#39;scale,HAMD)and Hamilton anxiety scale(Hamilton anxiety scale,HAMA);Curative effect evaluation by gastrointestinal symptoms rating scale(gastrointestinal symptom rating scale,GSRS).ResultsTwo groups after treatment, HAMD scores and HAMA scores was decreased(P〈0.05),the treatment group improved more significantly(P〈0.05)than the control group;The effective rate of 90% of treatment group was obviously higher than that of 63.75% in the control group. ConclusionThe use of antidepressant drugs and anti-anxiety drugs can significantly improve the curative effect of functional dyspepsia.
出处
《基层医学论坛》
2015年第34期4767-4768,共2页
The Medical Forum
关键词
功能性消化不良
精神心理因素
抗抑郁药
抗焦虑药
Functional dyspepsia
The spirit of psychological factors
Anti-depressant drugs
Anti-anxiety drugs