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银杏叶提取物防治心脑血管疾病的研究进展 被引量:57

Research progress of Ginkgo biloba extract for cardiovascular and cerebrovascular diseases
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摘要 银杏叶提取物(Ginkgo biloba extract)是目前国际上使用最为广泛的中药提取物之一,主要活性成分是银杏黄酮和银杏内酯类化合物。心脑血管疾病是全球主要的病死原因,对其防治具有重要的意义。近年来的研究表明,银杏叶提取物对心脑血管疾病的防治有多环节、多靶点、不良反应小的优势,应用前景良好。因此,本文综述了近年来银杏叶提取物对心脑血管疾病的防治作用和机制。 Ginkgo biloba extract is one of the most widely used herbal extracts,and its main active components are Ginkgo biloba flavonoids and ginkgolides. Cardiovascular and cerebrovascular diseases are the leading causes of death globally,so their prevention and treatment have important significance. Recent studies show that Ginkgo biloba extract is widely used to treat cardiovascular and cerebrovascular diseases. Ginkgo biloba extract has advantages such as acting at multi levels and multi targets and having little side effects,which has a vast application prospect. This paper reviewed the effects and mechanisms of Ginkgo biloba extract on cardiovascular and cerebrovascular diseases.
出处 《中国新药杂志》 CAS CSCD 北大核心 2016年第1期76-81,共6页 Chinese Journal of New Drugs
基金 国家自然科学基金(81200152) 河北省医学科学研究重点课题(20090383 20100035 20100333)
关键词 银杏叶提取物 心血管疾病 脑血管疾病 EGB 761 Ginkgo biloba extract cardiovascular diseases cerebrovascular diseases EGb 761
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  • 1JI W, MA X, XIE H, et al. Molecularly imprinted polymers with synthetic dummy template for simultaneously selecti,,'e removal and enrichment of ginkgolic acids from Ginkgo biloba L. leaves extracts [ J ]. J Chromatogr A,2014 ( 1368 ) :44 - 51.
  • 2RENNER SS. Evolution. Living fossil younger than thought[ J]. Science, 2011, 334(6057): 766-767.
  • 3孙国明,巩丽丽,周严严,容蓉,田景振.正交试验设计优选银杏内酯体外纤溶活性最佳配比[J].中国新药杂志,2014,23(9):1015-1018. 被引量:2
  • 4陈梅霞,苏洁,张玥莉,陈素红,吕圭源.银杏叶提取物与银杏黄酮对高脂血症大鼠血脂水平影响的比较研究[J].中国新药杂志,2014,23(7):833-838. 被引量:37
  • 5WANG W ,KANG Q ,LIU N ,et al. Enhanced dissolution rate and oral bioavailability of Ginkgo biloba extract by preparing solid dis- persion via hot-melt extrusion [ J ]. Fitoterapia, 2015 ( 102 ) : 189 - 197.
  • 6HAO PP, JIANG F, CHEN YG, et al. Traditional Chinese med- ication for cardiovascular disease[ J]. Nat Rev Cardiol, 2015, 12 (2) :115 -122.
  • 7郑希杰,徐运.银杏叶提取物治疗急性脑梗死的研究进展[J].中西医结合心脑血管病杂志,2014,12(5):617-618. 被引量:22
  • 8WU Y, LI S, CUI W, et al. Ginkgo biloba extract improves coro- nary blood flow in patients with coronary artery disease: role of endothelium-dependent vasodilation[ J ]. Planta Med, 2007, 73 (7) : 624 -628.
  • 9WU Y, LI S, ZU X, et al. Ginkgo biloba extract improves coro- nary artery circulation in patients with coronary artery disease: contribution of plasma nitric oxide and endothelin-1 [ J]. Phyto- ther Res, 2008, 22(6) :734 -739.
  • 10WU Y, LI S, CUI W, et al. Ginkgo biloba extract improves coro- nary blood flow in healthy elderly adults: role of endothelium-de- pendent vasodilation [ J ]. Phytomedicine, 2008, 15 ( 3 ) : 164 - 169.

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