首次脑梗死与复发性脑梗死危险因素分析

Analysis of risk factors for cerebral infarction and hemorrhage

目的:观察首次脑梗死与复发性脑梗死的危险因素,为脑卒中及其复发的预防提供依据。方法:采用病例对照研究设计,首次脑梗死与复发性脑梗死进行对比。收集病例资料,采用多元Logistic回归分析方法分别对脑梗死及复发性脑梗死危险因素进行分析。结果:常见危险因素中,年龄较大(OR=0.92,95%CI[0.88,0.96])和2型糖尿病史(OR=0.14,95%CI[0.03,0.63])患脑梗死的风险更大;而复发性脑梗死中较重要的危险因素为年龄较大(OR=1.03,95%CI[1.00,1.05])、有高血压基础病(OR=2.42,95%CI[1.28,4.56])、家族史(OR=2.22,95%CI[1.24,3.99])更易复发,而温和型性格却为复发性脑梗死的保护因素(OR=0.48,95%CI[0.28,0.82])。结论:首次脑梗死与复发性脑梗死比较重要的危险因素不同,但年龄为共同相关因素。

Objective：To investigate the risk factors for cerebral infarction and recurrent cerebral infarction and provide the basis for the prevention of cerebral apoplexy and its recurrence.Methods：A case-control study design was used to compare cerebral infarction with cerebral hemorrhage and compare cerebral infarction with recurrent cerebral infarction.The data collected from clinic was used to analyze the risk factors for cerebral infarction and recurrent cerebral infarction by Logistic regression analysis.Results：Among the common risk factors,older age（OR=0.92,95%CI[0.88,0.96]） and type 2 diabetes mellitus（OR=0.14,95%CI[0.03,0.63]） were greater risk factors for cerebral infarction.And,risk factors including older age（OR=1.03,95%CI[1.00,1.05]）,hypertension underlying diseases（OR=2.42,95%CI[1.28,4.56]）,family history（OR=2.22,95%CI[1.24,3.99]） that were more susceptible to the recurrent cerebral infarction.Mild personality,however,would contribute to prevent the recurrent cerebral infarction（OR=0.48,95%CI[0.28,0.82]）.Conclusion：Cerebral infarction and recurrent cerebral infarction have differences in higher risk factors,but share age-related factors in common.