腹腔镜下卵巢囊肿剥除术前后抗苗勒氏管激素与基础促卵泡刺激素水平的变化与临床价值

The level changing and clinical value of AMH and bFSH before and after laparoscopic ovarian cystectomy

目的对腹腔镜下行卵巢囊肿剥除术患者在手术前和手术后的抗苗勒氏管激素(AMH)和基础促卵泡刺激素(b FSH)含量进行测定,分析其临床意义和价值。方法将2012年1月-2014年1月该院妇产科就诊的34例卵巢巧克力囊肿患者作为研究组,并选取同期36例非巧克力囊肿患者作为对照组,两组患者均实施腹腔镜下卵巢囊肿剥离术进行治疗,并分别在手术前和手术完毕时对患者的AMH和b FSH水平进行测定。结果两组患者术后的AMH含量显著低于术前,差异具有统计学意义(P<0.05),研究组下降水平更明显;研究组患者术后的b FSH水平高于术前,差异具有统计学意义(P<0.05),而对照组患者术后血清b FSH含量同术前比较并未明显上升,差异无统计学意义(P>0.05)。结论行腹腔镜卵巢囊肿剥除术能够使患者的卵巢储备能力下降,测定AMH水平能够更好的反应出卵巢手术后卵巢储备状况。

【Objective】To determine the level of AMH and bFSH of the patients that implemented laparoscopic ovarian cystectomy before and after operation and analyze its clinical significance and value.【Methods】34 cases of ovarian chocolate cyst patients from January 2012 to January 2014 as the study group, the patients by the relevant examination body condition conforms to the requirements of laparoscopic operation, and selected 36 cases of non chocolate cyst patients as control group, patients of the two groups underwent laparoscopic ovarian cystectomy for the treatment, and AMH and bFSH level were measured before and after operation. 【Results】The postoperative AMH of the two groups was significantly lower than that before operation, with statistical difference（P〈0.05）, decreased the level of study group was more obvious; bFSH level in study group after operation is higher than the level before operation, with statistical difference（P〈0.05）, while the serum bFSH of patients in control group did not increased significantly, with no significant difference（P〉0.05）. 【Conclusion】Laparoscopic ovarian cyst stripping can decrease the ovarian reserve ability, and the AMH level can better reflect ovarian reserve status after ovarian surgery.