青春双歧杆菌酸奶治疗妊娠期便秘的临床观察

Effects of yoghurt with live bifidobacterium adolescentic on pregnant women with constipation

目的观察和评价青春双歧杆菌酸奶治疗妊娠中、后期便秘的临床疗效。方法将152例妊娠期便秘患者随机分为治疗组和对照组,均给予基础治疗,治疗组同时每天晚饭后1h饮用200 mL最低活菌浓度在108 cfu/mL以上的青春双歧杆菌酸奶,10d后观察疗效。结果治疗组治疗总有效率为97.37%,显著高于对照组的51.32%(P<0.01),治疗组大便频率提高到每周4.60±2.01次,显著高于对照组的每周2.95±1.05次(P<0.01),治疗组无不良反应。结论青春双歧杆菌酸奶治疗妊娠中、后期便秘疗效显著。

Objective To observe and evaluate the effect of bifidobacterium adolescentic yoghurt to treat constipation in pregnant women.Methods 152 pregnant women with constipation were randomly divided into treatment group（n=76）and control group（n=76）.Both groups were given basic treatment.In treatment group,200 mL yoghurt which minimum living bifidobacterium adolescentic concentration was above 108 cfu/mL was drunk once a day.The effect of treatment was observed 10 days later.Results The total effective rate of treatment group was 97.37%,which was significantly higher than 51.32% which was the total effective rate of the control group（P〈0.01）,and the defecate frequency in treatment group was 4.60±2.01 times per week which was significantly higher than2.95±1.05 times per week which was the defecate frequency of the control group（P〈0.01）.Conclusion Bifidobacterium adolescentic yoghurt is remarkably effective to treat constipation in gestation period.