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血管介导下的神经细胞迁移 被引量：1

Study progresses in vasculature guided neural migration
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摘要 中枢神经系统发育过程中已经确定的神经细胞迁移模式主要有两种:根据迁移方向和脑表面的关系分为放射状迁移和切线迁移。而根据神经细胞迁移过程中,为其提供支架介导作用的细胞的特性则可以划分为:胶质性迁移、神经元性迁移、血管性迁移。大量研究表明,血管在神经细胞迁移过程中发挥着重要作用,血管性迁移受很多因素影响,如脑源性神经营养因子、血管趋化因子以及血管内皮生长因子,探讨大脑发育中神经细胞的迁移方式,尤其血管性迁移中各因子的作用机制则是本文的要旨。 According to the moving direction of neural migration,the radial migration and tangential migration can be assorted.However,neural migration can also be classified into glial migration,neuronal migration and vasophilic migration,depending on various migrating medium.A large number of studies revealed that vasophilic migration has played important roles in brain development and disease genesis.There are many factors to affect vasophilic neural migration,such as brain-derived neurotrophic factor,vascular chemokines,and vascular endothelial growth factor and so on.In this review,we will mainly introduce some biological properties of vasophilic neural migration in the developing brain,and particularly the mechanism of various factors to affect vasophilic migration will be discussed as well.
作者 梁红霞 李依芃 时书勤 邓锦波
机构地区 河南大学护理学院神经生物学研究所 河南大学生命科学学院
出处 《河南大学学报（医学版）》 CAS 2015年第4期285-289,共5页 Journal of Henan University:Medical Science
基金 国家自然科学基金(31070952 U1204311)
关键词 血管 迁移 血管趋化因子 BDNF VEGF vasculature migration vascular chemokines BDNF VEGF
分类号 R329 [医药卫生—人体解剖和组织胚胎学]
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参考文献37

  • 1Marin O, Rubenstein J L. A long, remarkable journey, tangential migration in the telencephalon[-J~. Nat Rev Neurosci, 2001,2 : 780-- 790.
  • 2Rakic P. Guidance of neurons migrating to the fetal mon- key neocortex]-J-]. Brain Res 1971,33(2) :471--476.
  • 3Anton E S, Cameron R S, Rakic P. Role of neuron-glial junctional domain proteins in the maintenance and termi- nation of neuronal migration across the embryonic cere- bral wallEJ~. J Neurosci 1996,16(7)..2283--2293.
  • 4Edmondson J C, Hatten M E. Glial-guided granule neu- ron migration invitro: a high-resolution time-lapse video microscopic study[J]. J Neurosci, 1987,7(6):1928-- 1934.
  • 5Kriegstein A R, Noctor S C. Patterns of neuronal migra- tion in the embryonic cortex[J]. Trends Neurosci, 2004, 27(7) :392--399.
  • 6Noctor S C, Flint A C, Weissman T A, et al. Dammer- man RS, Kriegstein AR. Neurons derived from radial glial cells establish radial units in neocortex[J]. Nature, 2001,409(682l) :714--720.
  • 7Edmondson J C, Liem R K, Kuster J E, et al. Astrotac- tin.. a novel neuronal cell surface antigen that mediates neuron-astroglial interactions in eerebellar microcultures [J]. J Cell Biol, 1988,106(2) :505--517.
  • 8Anton E S, Kreidberg J A, Rakic P. Distinct functions of alpha3 and alpha(v) integrin receptors in neuronal migra- tion and laminar organization of the cerebral cortex[J]. Neuron, 1999,22(2) :277--289.
  • 9Perett and gli subven o P, Giachino C, altube assembly i tricular zone of t Neurol, Ono K, Aimar P, et al. Chain formation n the shift from neonatal to adult he rodent forebrain[-J]. J Comp 2005,487(4)~407--427.
  • 10Tomasiewicz H, Magnuson mutation inhibits tangential neuronal phenocopied by enzymatic removal of Neuron, 1994,13(3) :595--609. T, et al. N- migration polysialic aci.

二级参考文献90

  • 1Chilton JK.Molecular mechanisms of axon guidance.Dev Biol2006;292(1):13-24.
  • 2Niisslein-Volhard C,Wieschaus E,Kluding H.Mutations affecting the pattern of the larval cuticle in Drosophila melanogaster I.Zygotic loci on the second chromosome.Roux’s Arch Dev Biol1984;193:267-282.
  • 3Rothberg JM,Hartley DA,Walther Z,Artavanis-Tsakonas S.slit:an EGF-homologous locus of D.melanogaster involved in the development of the embryonic central nervous system.Cell1988;55(6):1047-1059.
  • 4Brose K,Bland KS,Wang KH,Arnott D,Henzel W,Goodman CS,Tessier-Lavigne M,Kidd T.Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance.Cell1999;96(6):795-806.
  • 5Hu H.Chemorepulsion of neuronal migration by Slit2in the developing mammalian forebrain.Neuron1999;23(4):703-711.
  • 6Ozdinler PH,Erzurumlu RS.Slit2,a branching-arborization factor for sensory axons in the mammalian CNS.J Neurosci2002;22(11):4540-4549.
  • 7Zhang B,Dietrich UM,Geng JG,Bicknell R,Esko JD,Wang L.Repulsive axon guidance molecule Slit3is a novel angiogenic factor.Blood2009;114(19):4300-4309.
  • 8MacMullin A,Jacobs JR.Slit coordinates cardiac morphogenesis in Drosophila.Dev Biol2006;293(1):154-164.
  • 9Mertsch S,Schmitz N,Jeibmann A,Geng JG,Paulus W,Senner V.Slit2involvement in glioma cell migration is mediated by Robo1receptor.J Neurooncol2008;87(1):1-7.
  • 10Hao JC,Yu TW,Fujisawa K,Culotti JG,Gengyo-Ando K,Mitani S,Moulder G,Barstead R,Tessier-Lavigne M,Barg-mann CI.C.elegans slit acts in midline,dorsal-ventral,and anterior-posterior guidance via the SAX-3/Robo.

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河南大学学报（医学版）
2015年 第4期

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