期刊文献+

血管钙化临床研究进展

原文传递
导出
摘要 血管钙化曾被认为仅是一种随钙磷在血管壁沉积后出现的“被动”过程,但近年来研究揭示,血管钙化具有与“骨形成”相似的分子调控机制。并有越来越多的临床证据表明,血管钙化与糖尿病、慢性肾病、心血管病等疾病的进展密切相关。因此,针对血管钙化的调控,有望为改善上述疾病的预后带来新的治疗思路。本文对血管钙化的临床研究进展作一回顾。
作者 肖幸 张存泰
出处 《医学新知》 CAS 2015年第6期371-373,375,共4页 New Medicine
关键词 血管 钙化 研究
  • 相关文献

参考文献30

  • 1Lanzer P, Boehm M, Sorribas V, et al. Medial vascular calcification revisited : review and perspectives [ J ]. Eur Heart J, 2014,35 ( 23 ) : 1515-1525.
  • 2Zhu D, Mackenzie N C,Farquharson C,et al. Mechanisms and clini- cal consequences of vascular calcification [ J ]. Front Endocrinol ( Lau- sanne) ,2012,3:95.
  • 3Allison M A, Criqui M H, Wright C M. Patterns and risk factors for systemic calcified atherosclerosis[ J]. Arterioscler Thromb Vasc Biol, 2004,24(2) :331-336.
  • 4Fuchs U, Caffier P, Schulz H G, et al. Arterial calcification in diabet-ics[ J]. Virchows Arch A Pathol Anat Histopathol, 1985,407 (4): 431-439. ".
  • 5Arad Y, Spadaro L A, Goodman K, et al. Prediction of coronary events with electron beam computed tomography [ J ]. J Am Coll Cardiol, 2000,36(4) :1253-1260.
  • 6Otsuka F, Sakakura K, Yahagi K, et al. Has our understanding of cal- cification in human coronary atherosclerosis progressed? [ J]. Arterio- scler Thromb Vasc Biol,2014,34 (4) :724-736.
  • 7Rutsch F, Nitschke Y, Terkehaub R. Genetics in arterial calcifica- tion:pieces of a puzzle and cogs in a wheel[ J ]. Circ Res,2011,109 (5) :578-592.
  • 8London G M, Guerin A P, Marchais S J, et al. Arterial medial calcifi- cation in end - stage renal disease : impact on all - cause and cardio- vascular mortality[ J ]. Nephrol Dial Transpl,2003,18 : 1731-1740.
  • 9Paulus W J, Tsch-pe C. A novel paradigm for heart failure with pre- served ejection fraction: comorbidities drive myocardial dysfunction and remodeling through coronary microvascular endothelial inflamma- tion[ J]. J Am Coil Cardiol,2013 ,62 :263-271.
  • 10Hjortnaes J, New S E, Aikawa E. Visualizing novel concepts of cardi- ovascular calcification [ J ]. Trends Cardiovasc Med, 2013,23 : 71-79.

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部