经支气管内超声引导针吸活检术在肺及纵隔占位性病变诊断中的价值

Diagnostic Value of Endobronchial Ultrasound Guided Transbronchial Needle Aspiration in Lung and Mediastinum Space Occupying Lesions

目的总结探讨经支气管内超声引导针吸活检术（EBUS—TBNA）对肺及纵隔占位性病变诊断的价值。方法对154例经CT证实的肺及纵隔占位性病变患者行EBUS—TBNA检查，并对穿刺物进行细胞学涂片和组织病理学分析。结果154例活检标本，有组织学对照的147例。细胞学检查发现恶性病变109例，可疑癌5例，良性病变9例。联合组织学及临床共同诊断对照，细胞学的敏感度95．5％，特异度100％，总准确率95．9％。结论细胞学联合组织学在EBUS—TBNA中对诊断肺和纵隔占位性病变及其分期具有准确、敏感、特异的优点。

Objective To evaluate the diagnostic value of endobronehial ultrasound guided transbronchial needle aspiration（ EBUS- TBNA）in lung and mediastinum space occupying lesions. Methods 154 patients with lung and mediastinum space occupying lesions found by CT underwent EBUS - TBNA. All samples were analyzed by cytological smears and histopathological exminations. Results Among the 154 biopsy specimens, 147 cases had histological com- parison. 109 cases were diagnosed as malignant lesions, 9 cases as benign lesions and 5 cases as suspicious carcino- ma. Overall sensitivity,specificity and accuracy were 95.5% , 100% and 95.9% respectively using histologic＇,.d and clinical diagnosis. Conclusion The combination of cytology and histology in EBUS - TBNA is accurate, sensitive and specific for diagnosis and staging lung and mediastinum space occupying lesions.