重症感染合并血小板减少症的影响因素及其相关性分析

Influence factors and correlation analysis for thrombocytopenia combine with severe infection

目的探讨ICU危重感染患者并发血小板减少症的影响因素,为临床防治和对患者预后的判断提供参考依据。方法回顾性分析2014年5月至2014年12月收住该院重症医学科的76例重症感染患者(男39例,女37例)的资料。以并发血小板减少症为A组(40例),无血小板减少症为B组(36例),考察重症感染患者并发血小板减少症的影响因素及预后差异。结果患者年龄、白细胞计数、中性粒细胞比例、革兰阴性菌感染、呼吸系统感染与重症感染患者并发血小板减少症具有相关性(P<0.05),两组患者ICU停留时间和病死率差异有统计学意义(P<0.05)。结论临床需重视对危重感染患者的血小板计数监测,对年龄大、因呼吸系统感染尤其合并有革兰阴性菌感染的患者,应重点干预和及时发现问题予以防治以改善其不良预后。

Objective To explore the influence factors of thrombocytopenia in patients with severe infection in ICU, so as to provide a reference for clinic prevention and treatment and the judgment of prognosis. Methods 76 patients（39 male, 37 female） with severe infection from May 9.014 to December 2014 were retrospectively analyzed in this hospital. Among them there were 40 cases with thrombocytopenia （Group A）, and 36 patients without thrombocytopenia （group B）. Influence factors and prognosis differences were investigated for thrombocytopenia combine with severe infection. Results There was correlation between the age, numeration of leukocyte,neutrophil ratio, gram negative bacteria infection, respiratory infection and severe infection combine with thrombocytopenia（P〈 0. 05）. ICU dwell time and mortality differences between the two groups was statistic significance （P〈 0.05）. Conclusion Platelet count should be monitored in patients with severe infection,especially in those with old age,respiratory infections, Gram negative bacteria infection, we should give priority intervention and find the point in time in order to prevention and cure and improve its poor prognosis.