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关节镜下滑膜切除对膝关节类风湿性滑膜炎患者血清TNF-α、IL-1及IL-6水平的影响 被引量:10

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摘要 目的 观察关节镜下滑膜切除治疗膝关节类风湿性滑膜炎患者血清中TNF-α、IL-1和IL-6的水平变化。方法 30例膝关节类风湿性滑膜炎患者行关节镜下滑膜切除术,检测治疗前后外周血TNF-α、IL-1及IL-6的水平变化,并根据Lysholm评分进行膝关节功能评估。结果 30例患者均获得4周~6个月随访,未出现感染、下肢静脉血栓等并发症。与治疗前相比,治疗后TNF-α、IL-1和IL-6水平降低,而膝关节Lyshlom评分增加(P〈0.05)。结论 关节镜下滑膜切除治疗膝关节类风湿性滑膜炎能明显降低TNF-α、IL-1及IL-6水平,改善患者膝关节功能。
作者 林小平 蒋青
出处 《江苏医药》 CAS 2016年第1期88-89,共2页 Jiangsu Medical Journal
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