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多囊卵巢综合征血浆生物标志物研究进展 被引量：2

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摘要 多囊卵巢综合征（polycystic ovary syndrome,PCOS）是青春期及育龄期女性最常见的内分泌紊乱性疾病。PCOS患病率高达5%～10%,临床表现为月经异常、不孕、高雄激素血症、卵巢多囊样等,同时可伴有肥胖、胰岛素抵抗、血脂异常。PCOS患者由于其异常的激素环境,使得患2型糖尿病、心脑血管病及子宫内膜癌的风险大大增加,严重影响患者的生活质量。
作者 高霞 唐奕 蔡素芬 龚斐
机构地区 中南大学基础医学院生殖与干细胞工程研究所 长治医学院附属和平医院妇产科
出处 《长治医学院学报》 2015年第6期473-476,共4页 Journal of Changzhi Medical College
关键词 多囊卵巢综合征 生殖激素 生物标志物
分类号 R711.75 [医药卫生—妇产科学]
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参考文献31

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  • 2崔琳琳,陈子江.多囊卵巢综合征诊断标准和诊疗指南介绍[J].国际生殖健康／计划生育杂志,2011,30(5):405-408. 被引量：293
  • 3Koninger A, Koch L, Edimiris P, et al. Anti Mullerian Hormone: an indicator for the severity of polycystic ovarian syndrome. Arch Gynecol Obstet, 2014,290 ( 5 ) : 1023-1030.
  • 4Munzker J, Hofer D, Trummer C,et al. Testosterone to di- hydrotestosterone ratio as a new biomarker for an adverse metabolic phenotype in the polycystic ovary syndrome. J Clin Endocrinol Metab, 2015,100(2) : 653 -660.
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二级参考文献18

  • 1Zawadski A,Dunaif A.Diagnostic criteria for polycystic ovary syndrome; towards a rational approach[M] /Dunatf A,Givens JR,Haseltine F.Polycystic Ovary Syndrome.Boston Blackwell Scientic,1992:377-384.
  • 2Rotterdam ESHRE/ASRM-Sponsored PCOS consensus worlcshop group.Revised 2003 consensus on diagnostic criteria and longterm health risks related to polycystic ovary syndrome(PCOS)[J].Hum Reprod,2004,19(1):41-d7.
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  • 5Thessaloniki ESHRFJASRM Sponsored PCOS Consensus Workshop Group.Consensus on infertility treatment related to polycystic ovary syndromef.Hum Reprod,2008,23(3):462-477.
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  • 10Solano M E, Sander V A, Ho H, et al.Systemic inflammation, cellu- lar influx and up-regulation of ovarian VCAM-1 expression in a mouse model of polycystic ovary syndrome (PCOS) [J].J Reprod Immunol, 2011, 92(1-2) : 33-44.

共引文献293

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二级引证文献29

长治医学院学报
2015年 第6期

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