血清25-羟维生素D水平与老年复发性脑梗死的相关性研究

Correlation between relapse of cerebral infarction in elderly patients and 25-hydroxyvitamin D levels

目的探讨血清25-羟维生素D[25（0H）D]水平与老年脑梗死复发的相关性。方法收取复发性脑梗死患者血液标本95例，稳定期脑梗死患者90例，同期健康体检者血液标本86例作对照（对照组），比较3组间血清25．羟维生素D水平之间的差异。结果复发性脑梗死组25-羟维生素D的水平明显低于稳定期脑梗死组和正常对照组，差异有统计学意义（P〈0．05）。结论血清25-羟维生素D水平下降与老年脑梗死复发密切相关，血清25-羟维生素D水平可以作为预测老年患者脑梗死复发的客观指标。

Objective To evaluate the correlation between the serum levels of 25-hydroxyvitamin D and the recurrence of cerebral infarction in elderly patients. Methods This study enrolled 95 patients in relapse stage of cerebral infarction, 90 patients in stable stage and 86 cases of normal controls, and the serum levels of 25-hydroxyvitamin D of every group were compared with each other. Results Compared with the group of the stable stage of cerebral infarction and normal controls, the levels of 25-hydroxyvitamin D in relapse stage of cerebral infarction group were obviously lower （P 〈 0.05）. Conclusion Serum levels of 25-hydroxyvitamin D were related to the recurrence of cerebral infarction in elderly patients, which indicated that the serum 25-hydroxyvitamin D was a useful marker for predicting the recurrence of cerebral infarction.