多重耐药鲍曼不动杆菌感染治疗策略与展望

The treatment strategies and outlooks of multidrug-resistant Acinetobacter baumannii infections

青霉素问世后抗菌药物便成为人类战胜病菌的强大武器,但是随着抗菌药物的广泛使用,尤其不合理使用,逐渐出现多重耐药甚至泛耐药菌株,并造成感染流行,给临床感染治疗带来严峻挑战。在新的有效的抗菌药物问世前,如何使用现有的抗菌药物进行治疗及寻求新的治疗策略是目前研究和应用的热点。本文就多重耐药鲍曼不动杆菌感染的抗菌药物治疗现状及新的治疗策略做一述评。

Antibiotics have been major weapon in medicine＇s war on bacterial infectious diseases since penicillin was discovered. Multi-drug resistant bacteria show up more and more because the varieties of antibiotics are used widely or irrationally, which have brought severe challenges to the chemotherapy in clinical infectious diseases. Before the new powerful antimicrobial drugs available, rational use of existing antimicrobials and optimization treatment strategies are al- ways the hot topics. This review concludes the up to date status of treatment and new treatment strategies for multi-drug resistant Acinetobacter baumannii infections.