养肝补肾方结合辛伐他汀治疗高脂血症临床观察

Clinical Observation of Liver Nourishing and Kidney Reinforcing Formula with Simvastatin on Hyperlipidemia

目的:观察养肝补肾方结合辛伐他汀治疗高脂血症的临床效果。方法:将120例高脂血症患者抽签随机分为治疗组与对照组,两组均为60例。对照组给予辛伐他汀治疗,治疗组给予自拟养肝补肾方结合辛伐他汀治疗,比较两组血脂指标变化及临床疗效。结果:治疗后两组各指标均下降,且治疗组TC、TG、LDL-C分别为(5.21±1.03)mmol/L、(1.74±0.86)mmol/L、(3.05±0.67)mmol/L,显著低于对照组(5.82±1.24)mmol/L、(2.23±1.44)mmol/L、(3.69±0.73)mmol/L(P<0.05);HDL-C(1.87±0.88)mmol/L较对照组(1.32±0.67)mmol/L高,差异具有统计学意义(P<0.05);治疗组总有效率为95.0%,高于对照组78.3%,差异具有统计学意义(P<0.05)。结论自拟养肝补肾方结合辛伐他汀治疗高脂血症疗效确切,改善血脂指标显著。

Objective： To observe the clinical effect of liver nourishing and kidney reinforcing formula combined with simvastatin on hyperlipidemia. Methods ：120 patients with hyperlipidemia were randomly divided into treatment group and control group, each group of 60 cases. The control group was treated with simvastatin, while the treatment group was treated with self-made liver nourishing and kidney reinforcing formula combined with simvastatin. For both groups, a month was taken as a course of treatment. After two courses of treatment, the clinical effects and the related indexes were evaluated. Results： After treatment, all various indexes of both groups were decreased. TC, TG, LDL-C of treatment group were respectively （5.21 ± 1.03 ） mmol/L, （1.74 ±0.86） mmol/ L, （3.05 ±0. 67） mmol / L, and significantly lower than corresponding （5.82 ±1.24）mmol/L, （2. 23 ±1.44） mmol / L, （3. 69 ± 0. 73 ）mmol / L （P 〈 0. 05 ） in control group. HDL - C （ 1.87 ±0. 88） mmol/ L of treatment group was higher than （ 1.32 ±0.67） mmol / L of control group, the difference was statistically significant （P 〈0. 05）. The total effective rate of treatment group was 95.0%, and higher than 78.3% of control group, the difference was statistically significant （ P 〈 0. 05 ）. Conclusion ： The clinical effect of liver nourishing and kidney reinforcing formula combined with simvastatin on hyperlipidemia is definited, the improvement of serum lipid indexes is significant.