伴房颤的急性脑梗死患者梗死灶分布特点及相关因素分析

Analysis of infarction distribution characteristics and related factors in acute cerebral infarction patients with atrial fibrillation

目的研究伴房颤的急性脑梗死患者梗死灶分布特点,并对患者的相关临床资料进行分析。方法回顾性分析78例伴房颤的急性脑梗死患者和123例单纯急性脑梗死患者临床和影像学资料,比较两组间性别构成、年龄、既往史、美国国立卫生研究院神经功能缺损评分(NIHSS)、脑梗死灶分布等差异。结果与单纯急性脑梗死患者比较,伴房颤的急性脑梗死患者入院NIHSS评分、年龄以及合并糖尿病、冠心病病史比例较高,梗死部位以累及前循环、右半球最为多见(均P<0.05),而在性别构成以及合并高血压、血脂异常比例方面无统计学差异(均P>0.05)。结论伴房颤的急性脑梗死患者较单纯急性脑梗死患者病情重,病灶多位于前循环和右半球,其发病与年龄以及合并糖尿病、冠心病病史密切相关。

Objective To study the distribution features and the clinical data of cerebral infarction in acute cerebral infarction patients with atrial fibrillation.Methods A retrospective analysis of clinical and imaging data was adopted among 78 acute cerebral infarction patients with atrial fibrillation and 123 acute cerebral infarction patients without atrial fibrillation.Gender composition,age,past history,the National Institutes of Health Stroke Scale（NIHSS）neurological function defect score and distribution of cerebral infarction lesions were compared between the two groups.Results The NIHSS score,age and the ratio of combining with diabetes,coronary heart disease history of the acute cerebral infarction patients with atrial fibrillation were higher than those of the acute cerebral infarction patients without atrial fibrillation.Anterior circulation and right hemispheric infarction were much more common in the acute cerebral infarction patients with atrial fibrillation（P〈0.05,respectively）.There were no significant differences in sex,hypertension,dyslipidemia between the two groups（P〉0.05）.Conclusions The condition of the acute cerebral infarction patients with atrial fibrillation were more severe than those without atrial fibrillation,and the lesions were more frequently located in the anterior circulation and the right hemisphere.The disease was closely correlated with age,diabetes and coronary heart disease.