单、双侧脑灌注技术在主动脉外科手术中脑保护效果的比较

Comparison of Brain Protective Effect Between Unilateral and Bilateral Cerebral Perfusion Technique in Aortic Surgery

目的:比较单、双侧顺行脑灌注技术在Stanford A型主动脉夹层手术中的效果和安全性。方法:120例急性复杂型Stanford A型主动脉夹层,其中51例采用单侧脑灌注技术、69例采用双侧脑灌注技术,统计病人死亡率及并发症率。结果:单侧脑灌注组与双侧脑灌注组总的院内死亡率分别为5.88%、4.35%,差异无统计学意义;中枢神经系统总并发症率分别为37.25%、17.39%,差异有统计学意义。结论:双侧脑灌注技术用于急性Stanford A型主动脉夹层优于单侧脑灌注,安全、简单。

Objective：To compare the effects of unilateral antegrade selective cerebral perfusion with bilateral antegrade selective cerebral perfusion in acute Stanford type A aortic dissection surgery.Methods：From January 2008 to January 2014,120 patients with acute Stanford type A aortic dissection receiving unilateral or bilateral antegrade selective cerebral perfusion,were divided into two groups according to the way of cerebral perfusion.The mean in-hospital mortality rate and neurological complication rate were analysed.Results：The in-hospital mortality rate was 5.88%and 4.35%respectively in unilateral and bilateral antegrade selective cerebral perfusion groups,and the difference was not statistically significant.The central nervous system complication rate was 37.25% and 17.39%,respectively,which was significantly different between the two groups.Conclusion：The technique of bilateral antegrade selective cerebral perfusion is better than the unilateral one,and it＇s safer and easier.