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大疱性类天疱疮临床评估指标的研究进展 被引量：12

Clinical measures of bnllous pemphigoid
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摘要 大疱性类天疱疮是一类自身免疫性疱病。针对自身免疫性大疱病，有专门的评分指标用以评估病情的严重程度和对治疗的反应。常用的评价指标有自身免疫性疱病严重程度评分，专门针对大疱性类天疱疮的大疱性类天疱疮疾病面积指数评分，以及其他的一些评分方式。自身免疫性大疱病严重程度评分已经经过了效度检验，广泛地应用在寻常型天疱疮和其他一些自身免疫性疱病的评估中。大疱性类天疱疮疾病面积指数评分尚处于检验的过程中，应用该评分的临床试验较少。上述两种评分方式均对全身的皮肤、黏膜皮损情况，主观瘙痒程度进行了评分。 Bullous pemphigoid （BP） is a group of autoimmune blistering skin diseases. There are special measures for the assessment of disease severity and therapeutic response in autoimmune bullous skin diseases. Common scoring indexes include autoimmune bullous skin disorder intensity score （ABSIS）, bullous pemphigoid disease area index （BPDAI）, and so on. ABSIS has been validated, and is widely applied in evaluation of pemphigus vulgaris and other autoimmune blistering diseases. BPDAI is still in the process of verification, and has been applied in only a few clinical trials. The evaluation of diseases by ABSIS and BPDAI is both based on a global assessment of skin and mucosal lesions, and degree of subjective pruritus.
作者 刘艺迪 左亚刚 李丽
机构地区 中国医学科学院北京协和医学院北京协和医院皮肤科
出处 《中华皮肤科杂志》 CAS CSCD 北大核心 2016年第1期65-68,共4页 Chinese Journal of Dermatology
基金 国家自然科学基金（81371731） 北京市自然科学基金（7132203）
关键词 类天疱疮 大疱性 自身免疫 疾病严重程度评分 大疱性类天疱疮疾病面积指数评分 临床评估指标 Pemphigoid, bullous Autoimmunity Severity of illness score Bullous pemphigoid disease area index Clinical outcome measures
分类号 R758.66 [医药卫生—皮肤病学与性病学]
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参考文献16

  • 1Chameux J, Lorin J, Vitry F, et al. Usefulness of BP230 and BP180-NC16a enzyme-linked immunosorbent assays in the initial diagnosis of bullous pemphigoid: a retrospective study of 138 patients[J]. Arch Dermatol, 2011,147(3 ): 286-291. DOI: 10.1001/ archdermatol.2011.23.
  • 2Feng S, Wu Q, Jin P, et al. Serum levels of autoantibodies to BP180 correlate with disease activity in patients with bullous pemphigoid [J]. Int J Dermatol, 2008, 47 (3): 225-228. DOI: 10.1111/j.1365- 4632.2008.03473.x.
  • 3Pfutze M, Niedermeier A, Hertl M, et al. Introducing a novel autoimmune bullous skin disorder intensity score (ABSIS) in pemphigus[J]. Eur J Dermatol, 2007,17 (1): 4-11. DOI: 10.1684/ ejd.2007.0090.
  • 4Daniel BS, Hertl M, Werth VP, et al. Severity score indexes for blistering diseases[J]. Clin Dermatol, 2012, 30( 1 ): 108-113. DOI: 10.1016/j.clindermatol.2011.03.017.
  • 5Rahbar Z, Daneshpazhooh M, Mirshams-Shahshahani M, et al. Pemphigus disease activity measurements: pemphigus disease area index, autoimmune bullous skin disorder intensity score, and pemphigus vulgaris activity score [J]. JAMA Dermatol, 2014, 150 (3): 266-272. DO/: 10.1001/iamadermatol.2013.8175.
  • 6张洁尘,冯素英,王宝玺.天疱疮疗效评估的研究进展[J].中华皮肤科杂志,2012,45(1):60-62. 被引量：5
  • 7Murrell DF, Daniel BS, Joly P, et al. Definitions and outcome measures for bullous pemphigoid: recommendations by an international panel of experts [J]. J Am Acad Dermatol, 2012, 66 ( 3 ): 479-485. DOI: 10.1016/j.jaad.2011.06.032.
  • 8Patsatsi A, Kyriakou A, Pavlitou-Tsiontsi A, et al. Association of autoantibodies to BP180 with disease activity in Greek patients with bullous pemphigoid [J]. Clin Dev Immunol, 2012, 2012: 854795. DOI: 10.1155/2012/854795.
  • 9Zhao CY, Murrell DF. Outcome measures for autoimmune blistering diseases[J]. J Dermatol, 2015, 42( 1 ): 31-36. DOI: 10.1111/1346-8138.12711.
  • 10Levy-Sitbon C, Barbe C, Plee J, et al. Assessment of bullous pemphigoid disease area index during treatment: a prospective study of 30 patients [J]. Dermatology, 2014, 229 (2): 116-122. DOI: 10.1159/000362717.

二级参考文献34

  • 1Torre GC. SCC antigen in malignant and nonmalignant squamous lesions [J]. Tumor Biology, 1998, 19(6) : 517 -526.
  • 2Duk JM, van Voorst Vader PC, Ten Hoor KA, et al. Elevated levels of squamous cell carcinoma antigen in patients with a benign disease of the skin[J]. Cancer, 1989, 64(8) : 1652 - 1656.
  • 3Campbell B, De'Ambrosis B. Squamous cell carcinoma antigen in patients with cutaneous disorders[J]. Journal of the American Academy of Dermatology, 1990, 22(4) : 639 -642.
  • 4Numahara T, Nakashima K, Yamamoto S, et al. Significance of squamous cell carcinoma-related antigen in psoriasis and generalized eczema. Preliminary report[J]. Dermatologica, 1989, 178(2) : 73 -74.
  • 5Kudo H, Yamamoto M, Miyachi Y, et al. Increased serum levels of squamous cell carcinoma-related antigen in pemphigus[J]. Br J Dermatol, 1988, 118(4) : 471 -474.
  • 6Takeda A, Higuchi D, Takahashi T, et al. Overexpression of serpin squamous cell carcinoma antigens in psoriatic skin [J]. Journal of Investigative Dermatology, 2002, 118 ( 1 ) : 147 - 154.
  • 7Mitsuishi K, Nakamura T, Sakata Y, et al. The squamous cell carcinoma antigens as relevant biomarkers of atopic dermatitis [ J ]. Clinical and Experimental Allergy, 2005, 35 (10) : 1327 -1333.
  • 8Gudi VS, White MI, Cruickshank N, et al. Annual incidence and mortality of bullous pemphigoid in the Grampian Region of North-east Scotland[J]. Br J Dermatol, 2005, 153(2) : 424 -427.
  • 9Nanda A, Al-Saeid K, Al-Sabah H, et al. Clinicoepidemiological features and course of 43 cases of bullous pemphigoid in Kuwait[J]. Clin Exp Dermatol, 2006, 31(3): 339-342.
  • 10Langan SM, Smeeth L, Hubbard R, et al. Bullous pemphigoid and pemphigus vulgaris-incidence and mortality in the UK: population based cohort study[J]. BMJ, 2008, 337 : a180.

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中华皮肤科杂志
2016年 第1期

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