摘要
目的:探讨急性ST段抬高型心肌梗死(STEM1)患者入院早期中性粒细胞/淋巴细胞比值(NLR)与院内主要不良心血管事件(MACE)的相关性。方法:回顾分析2010—01至2014—12我院接受急诊经皮冠状动脉介入治疗(PCI)的STEMI患者420例,分为发生院内MACE组(n=47)和正常出院组(n=273)。应用单因素及多因素Logistic回归分析评价NLR是否可以作为STEMI患者发生院内MACE的独立危险因素。结果:单因素Logistic回归分析提示:高NLR患者院内MACE发生率明显高于低NLR患者(比值比=3.19,95%可信区间:1.55—2.65,P=0.012)。多因素Logistic回归分析提示:高NLR是STEMI患者发生院内MACE的独立危险因素(比值比=3.05,95%可信区间:1.59~10.54,P=0.015)。结论:入院早期高NLR与STEMI患者发生院内MACE相关,是STEMI患者发生院内MACE的独立危险因素。
Objective: To explore the relationship between the ratio of neutrophil/lymphocyte (NLR) and in-hospital major adverse cardiac events (MACE) in patients with acute ST-elevation myocardial infarction (STEMI) at early admission. Methods: A total of 420 acute STEMI patients admitted and received primary PCI in our hospital from 2010-01 to 2014-12 were retrospectively studied. The patients were divided into 2 groups: In-hospital MACE group, n=47 and Normal discharged group, n=373. Uni- and multivariate analyses were conducted to assess whether high NLR is the independent predictor for in-hospital MACE occurrence. Results: Univariate regression analysis indicated that the occurrence rate of in-hospital MACE in high NLR patients were higher than those in low NLR patients (OR=3.19, 95% CI 1.55-2.65, P=0.012). Multivariate regression analysis showed that high NLR was the independent risk factor for in-hospital MACE occurrence in STEMI patients (OR=3.05, 95% CI 1.59-10.54, P=0.015). Conclusion: High NLR is the independent risk factor for in-hospital MACE occurrence in STEMI patients at the early admission.
出处
《中国循环杂志》
CSCD
北大核心
2016年第1期36-39,共4页
Chinese Circulation Journal