手指健智操治疗老年轻度认知功能障碍的效果

Curative effect of finger exercise of tranquilizing the mind and promoting the intelligence in the treatment of elderly mild cognitive impairment

目的探讨手指健智操对老年轻度认知功能障碍患者的临床疗效及其对脑血流的影响。方法将120例老年轻度认知功能障碍患者按照随机数字表法分为对照组与观察组，各60例。对照组予银杏叶片治疗，观察组在对照组的基础上予手指健智操辅助治疗，进行1年随访观察。采用经颅内多普勒（TCD）检查脑血流异常情况；采用简易精神状态检查量表（MMSE）、日常生活能力评定量表（ADL）进行认知功能量化评价。结果观察组总有效率为78．33％，而对照组为58．33％，提示观察组疗效明显优于单纯常规药物治疗对照组，两组比较差异有统计学意义（P〈0．05）。同时，观察组患者MMSE与ADL均低于对照组，且其较治疗前改善差值亦明显优于对照组（P〈0．05）。再者，观察组患者1年后TCD存在1项或以上异常的有31例（31／60，51．67％），明显优于对照组53例（53／60，88．33％），差异有统计学意义（P〈0．05）。结论手指健智操能够有效地辅助治疗CMI患者。通过改善其脑代谢功能，减缓遗忘型损害的发生与发展，具有安神益智的功效，方法简便，值得推广。

Objective To investigate the curative effect of finger exercise of tranquilizing the mind and promoting the intelligence in the treatment of elderly mild cognitive impairment （MCI） and its influence on cerebral blood flow. Methods 120 elderly patients with MCI were divided into control group and observation group according to the random number table with 60 cases in each group. Patients in control group were treated by ginkgo leaf tablets, and patients in observation group were treated by finger exercise which could tranquilize the mind and promote the intelligence based on the control group. Both two groups were observed for 1 year by follow-up visit. Transcranial doppler sonography （TCD） was applied to check the cerebral blood flow, and mini mental status examination（MMSE） and activity of daily living scale （ADL） were used to quantifiably evaluate the cognitive function. Results The total effective rate of observation group was 78.33%, and that of control group was 58.33%, with statistically significant difference （P〈0.05）. MMSE score and ADL score after treatment in observation group were both less than those in control group （P〈0.05）. In 1 year after treatment, there were 31 patients with abnormal results including 1 or more on the TCD in observation group, and there were 53 cases in control group, with statistically signifcant difference （P〈0.05）. Conclusions Finger exercise of tranquilizing the mind and promoting the intelligence has significant effect in the adjuvant therapy of MCI, which can improve metabolic function of the brain, reduce the occurrence and development of amnestic mild congnitive impairment, tranquilize the mind and promote the intelligence, worthy of clinical application.