摘要
目的探讨血浆PAI—1、CysC与2型糖尿病合并颈动脉粥样硬化的关系。方法用放射免疫法及生物化学法检测133例患者血浆PAI—1、胱抑素C水平。结果（1）2型糖尿病合并颈动脉粥样硬化组血浆PAI-1、胱抑素C水平与正常对照组、单纯2型糖尿病组比较差异有统计学意义俨〈0．05）。（2）回归分析显示：PAI-1、CysC与2型糖尿病合并颈动脉粥样硬化独立相关（OR=1．133、1．012E7，P〈0．01）。结论PAI-1、CysC与2型糖尿病合并颈动脉粥样硬化相关，可能成为2型糖尿病合并颈动脉粥样硬化患者的预测指标。
Objective To investigate the correlation between the levels of serum PAI-1, Cystatin C and carotid atherosclerosis in type 2 diabetic mellitus （T2DM） patients. Method Detected the levels of serum PAI-1 and Cystatin C with RIA and physiological chemistry in 133 T2DM patients. Results （1） The levels of serum PAI-1 and Cystatin C in patients with carotid atherosclerosis were significantly higher than those in patients without carotid atherosclerosis and control group （P〈0.05）. （2） Logistic analysis showed that the levels of serum PAI-1 and Cystatin C were independently related to carotid atherosclerosis in type 2 diabetic mellitus patients （OR= 1.133, 1.012E7; P〈0.01）. Conclusions PAI-1 and Cystatin C play the important role in carotid atherosclerosis in T2DM patients, which may be the forecast indexes of carotid atherosclerosis in T2DM patients.
出处
《国际医药卫生导报》
2016年第1期54-56,共3页
International Medicine and Health Guidance News
