糖尿病对PCI治疗预后的影响

Impact of diabetes mellitus on prognosis of PCI therapy

目的 观察糖尿病（DM）患者接受经皮冠状动脉介入治疗（PCI）的预后情况,评价DM对冠心病介入治疗预后的影响。方法 回顾性分析2012年7月-2014年6月于辽宁省大石桥市中心医院心内科收治的行PCI术的583例患者的临床资料,按是否合并DM分为DM组152例和非糖尿病（NDM）组431例,记录两组患者术后1年内再次心肌梗死、PCI术,冠状动脉旁路移植术及死亡等主要不良心血管事件（MACE）发生情况。结果 DM组1年死亡率为4.6%,显著高于NDM组的0.7%（P〈0.01）,DM组的再次心肌梗死率为12.5%,高于NDM组的6.3%（P〈0.01）,DM组的总心血管不良事件发生率为25.7%,高于NDM组的13.9%（P〈0.01）。结论 冠心病合并DM患者接受PCI术后发生MACE的比例较高,因此,尽管患者成功接受了PCI治疗,仍需重视糖尿病的进一步治疗,持续关注血糖、血脂。

Objective To observe the prognosis situation of diabetic patients accepted percutaneous coronary intervention（PCI） and to evaluate the impact of diabetes mellitus on prognosis of PCI. Methods Data of 583 patients conducted PCI in department of cardiology in Dashiqiao Central Hospital of Liaolin Province from July 2012 to June 2014 were retrospectively analyzed.Patients were divided into DM group（n=152） and NDM（n=431） group by wether combined with diabetes mellitus or not.The main adverse cardiovascular events（MACE） incidence situation liked miocardial infarction and PCI operation again,coronary artery bypass surgery and death in after 1 year operation in two groups were recorded. Results 1 year mortality rate in DM group was 4.6%,and it was obviously higher than that of NDM group（0.7%）（P〈0.01）.Miocardial infarction rate again was 12.5% in DM group,and it was higher than that of NDM group（6.3%）（P〈0.01）.The incidence rate of total adverse cardiovascular event in DM group was 25.7%,and it was higher than that of NDM group（13.9%）（P〈0.01）. Conclusion The ratio of coronary heart disease patients with diabetes mellitus occurred MACE after PCI is higher.So,although patients are given successfully underwent PCI therapy,it still needs to attach importance to the further treatment of diabetes,and continuous pay attention to blood sugar and blood fat.