雾化吸入联合激光疗法治疗儿童喘息性疾病的疗效观察

Effect observation of aerosol inhalation combined with laser therapy in the treatment of asthmatic disorder in children

目的探讨雾化吸入联合激光疗法治疗儿童喘息性疾病的效果。方法选择2013年2月-2015年2月在韶关市第一人民医院接受治疗的喘息性疾病患儿130例作为研究对象,随机分成两组,各65例。对照组给予雾化吸入复方异丙托溴铵溶液和布地奈德混悬液,观察组在对照组基础上联合双波长光纤激光治疗。观察并比较两组患儿肺部哮鸣与湿啰音、喘息、咳嗽消失时间,住院天数,免疫球蛋白指标（Ig M、Ig A、Ig G）水平。结果观察组肺部哮鸣与湿啰音消失时间为（3.08±1.15）d,喘息消失时间为（2.72±0.93）d,咳嗽消失时间为（3.85±0.46）d,住院天数为（5.36±1.65）d,均短于对照组的（4.76±1.58）、（4.04±1.35）、（5.33±1.22）、（7.59±2.03）d,差异均有统计学意义（P〈0.01）。观察组的Ig M为（1.65±0.45）g/L,Ig A为（2.78±0.55）g/L,Ig G为（10.76±1.56）g/L,均高于对照组的（0.98±0.32）、（1.75±0.41）、（7.87±1.30）g/L,差异均有统计学意义（P〈0.01）。结论雾化吸入联合激光疗法治疗儿童喘息性疾病能促进患儿症状体征的缓解,提高患儿的免疫抵抗力。

Objective To explore the effect of aerosol inhalation combined with laser therapy treating asthmatic disorder in children. Methods From February 2013 to February 2015,130 children with asthmatic disorder treated by our hospital were selected as research group and evenly divided into two groups in random.In control group,compound ammonium bromide solution and budesonide suspension was used,while in observation group,on the basis of control group,laser therapy of dual wavelength optical fiber was added.Disappearance time of wheezing rale and moist rale,panting,and coughing,hospital stay,and level of immune globulin indexes including Ig M,Ig A,and Ig G was observed and compared respectively. Results In observation group,disappearance time of wheezing rale,moist rale,panting and coughing,and hospital stay [（3.08 ±1.15） d,（2.72 ±0.93） d,（3.85 ±0.46） d,（5.36 ±1.65） d] was shorter than that in control group[（4.76±1.58） d,（4.04±1.35） d,（5.33±1.22） d,and（7.59±2.03） d respectively,which displayed statistical difference（P〈0.01）.In observation group,Ig M,Ig A,and Ig G [（1.65±0.45） g/L,（2.78±0.55） g/L,and（10.76±1.56） g/L] was higher than that in control group [（0.98 ±0.32） g/L,（1.75±0.41） g/L,（7.87 ±1.30） g/L],which displayed statistical significance（P〈0.01）.Conclusion Aerosol inhalation combined with laser therapy can enhance alleviation of symptoms and signs and improve immunoresistance in the treatment of asthmatic disorder in children.