三七参芪杞酒缓解体力疲劳功能的研究

Anti-fatigue Functions of Compound Panax Notoginseng Liquor

通过动物试验验证三七参芪杞酒缓解体力疲劳的功能。设置空白对照组与15%vol基酒对照组,以及5 m L/kg·BW、10 m L/kg·BW、15 m L/kg·BW 3个剂量组,受试小鼠每天按20 m L/kg·BW剂量经口灌胃1次,连续给予30 d后,分别进行负重游泳试验、血清尿素测定、肝糖原测定和血乳酸测定。结果表明,与15%vol基酒对照组比较,低、高剂量组小鼠的负重游泳时间显著延长(P<0.05、P<0.05),中、高剂量组小鼠的肝糖原含量显著升高(P<0.05、P<0.01),高剂量组小鼠运动后血乳酸含量显著降低(P<0.05)。三七参芪杞酒具有缓解体力疲劳的功能。

The anti-fatigue functions of compound Panax notoginseng liquor were verified by animal test. In the experiments, the mice were divided into three groups： blank control group, 15 %vol base liquor control group, and dose group （dosage of 5 mL/kg. BW, 10 mL/kg. BW, and 15 mL/kg · BW respectively, intragastric administration of 20 mL/kg · BW each day）. After 30 d, the mice were subjected to weight loading swimming test and their serum urea nitrogen, hepatic glycogen and serum lactic acid were measured. The results showed that, compared to 15 %vol base liquor control group, the weight loading swimming time of low-dose group and high-dose group was significantly prolonged （P〈 0.05, P〈0.05）, the hepatic glycogen content of middle-dose group and high-dose group was significantly increased （P 〈0.05, P 〈0.01）, and the serum lactic acid content of high-dose group was significantly decreased （P 〈 0.05） after swimming. Accordingly, compound Panax notoginseng liquor had anti-fatigue functions.