癫痫持续状态患儿的临床特点与影响近期疗效的相关因素分析

Clinical characteristics of children with status epilepticus and factors affecting its short-term effect

目的 分析癫痫持续状态（SE）患儿临床特点及其与对近期疗效的影响.方法 回顾性分析我院2013年1月至2015年1月收治的60例癫痫持续状态患儿病例资料,总结其临床特点,同时分析疾病临床特点与近期疗效的相关性.结果 3岁以下患儿SE发生率50.0％;病因以症状性为主,占68.3％;感染诱发SE最多,占61.7％;惊厥性SE发生率占86.7％;发作持续时间、控制时间分别以10 ～ 60 min、≤30 min为主,分别占80.0％、83.3％.近期疗效与SE发作持续时间、发作控制时间相关,差异有统计学意义（r值分别为0.58、0.76,P＜0.05）.结论 小儿癫痫持续状态发病以症状性病因为主,多由感染诱发,临床以惊厥性SE为主.SE近期疗效与SE发作持续时间及控制时间有关.

Objective To analyze the clinical characteristics of children with status epilepticus （SE） and the effect on the short-term effect.Methods The clinical data of 60 children with status epilepticus treated at our hospital from January, 2013 to January, 2015 were retrospectively analyzed.The clinical features were summarized.The correlation between the clinical characteristics of the disease and the short-term effect was analyzed.Results The incidence of SE was 50.0% in childrens under 3 years old.The main cause was symptomatic, accounting for 68.3%;most SE was induced by infection, accounting for 61.7%.The incidence of convulsive SE was 86.7%.The duration of attack and under-control time were 10-60 min and ≤ 30 min, accounted for 80.0% and 83.3%.The short-term efficacy correlated with the duration of attack and seizure control time, with statistical differences （r =0.58, 0.76, P 〈0.05）.Conclusions Most children with status epilepticus are induced by infection and mainly are convulsive SE.The short-term efficacy of SE correlates with the duration of attack and seizure control time.