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绝经后女性2型糖尿病患者股骨近端的骨强度

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摘要 骨密度是反映骨强度的公认指标,在一定程度上是骨折风险的预测因子,但其敏感性和特异性均不高。糖尿病尤其是2型糖尿病(T2DM)与骨质疏松的关系较为复杂,T2DM患者的骨密度可以正常或者降低,某些患者甚至出现增高。一系列的研究[1-3]证实,尽管T2DM患者的骨密度值较高,但其骨质疏松发生率和骨折风险却增高。基于对T2DM患者骨折风险与骨密度关系的认识尚不统一,本研究试图通过双能X线吸收仪(DXA)自带的髋结构分析软件研究T2DM患者股骨强度指数(FSI)、截面模数(SM)、横截面面积(CSA)、曲率比率(BR)等力学参数的变化规律,旨在从新的视角为T2DM患者脆性骨折的防治提供新的理论基础。
出处 《上海医学》 CAS CSCD 北大核心 2015年第11期847-849,共3页 Shanghai Medical Journal
基金 温岭市科技局资助项目(2010WLCB0085)
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参考文献18

  • 1ISHII S, CAULEY J A, CRANDALL C J, et al. Diabetes and femoral neck strength: findings from the Hip Strength Across the Menopausal Transition Study [ J ]. J Clin Endocrinol Metab, 2012, 97(1) : 190-197.
  • 2GARG R, CHEN Z, BECK T, et al. Hip geometry in diabetic women: implications for fracture risk [ J ]. Metabolism, 2012, 61(12): 1756-1762.
  • 3PRITCHARD J M, GIANGREGORIO L M, ATKINSON S A, et al. Association of larger holes in the trabecular bone at the distal radius in postmenopausal women with type 2 diabetes mellitus compared to controls I-J]. Arthritis Care Res (Hoboken), 2012, 64(1): 83-91.
  • 4周蕾,李冠武,常时新,薛峰,陈瑶,鲍虹,何庆,方巍,史晓.体脂量是绝经后女性股骨近端骨强度的决定因素(英文)[J].中国骨质疏松杂志,2014,20(2):145-151. 被引量:6
  • 5曾炳芳,李晓林,章振林.骨质疏松症和骨质疏松性骨折的挑战[J].上海医学,2011,34(3):161-163. 被引量:24
  • 6SAITO M, MARUMO K. Bone quality in diabetesFJ/OL]. Front Endoerinol (Lausanne), 2013, 4:72 [2013-06-141. http~//journal, frontiersin, org/artiele/10. 3389/fendo. 2013. 00072/full/.
  • 7马小静,孔祥雷,孟祥菊,董洁云,张静,张留歌,张倩倩,史宁宁.影响成年女性骨质疏松的相关因素研究[J].中国实用内科杂志,2014,34(S1):78-81. 被引量:2
  • 8张秀珍,宋利格,李红,韩峻峰,赵家胜,雷涛.2型糖尿病围绝经期妇女骨密度及骨代谢指标与糖、脂代谢的关系[J].上海医学,2006,29(4):203-206. 被引量:4
  • 9HAMILTON C J, JAMAL S A, BECK T J, et al. Evidence for impaired skeletal load adaptation among Canadian women with type 2 diabetes mellitus: insight into the BMD and bone fragility paradox[J]. Metabolism, 2013, 62(10): 1401- 1405.
  • 10BENHAMOU C L. Effects of osteoporosis medications on bone quality[J]. Joint Bone Spine, 2007, 74(1) : 39-47.

二级参考文献20

  • 1Rizzo M, Di Fede G, Mansueto P, et al. Statins and osteoporosis: myth or reality? Minerva Med, 2004, 95:521-527.
  • 2Gregorio F, Cristallini S, Santeusanio F, et al. Osteopenia associated with non-insulin-dependent diabetes mellitus: What are the causes? Diabetes Res Clin Pract, 1994, 23:43-54.
  • 3Luegmayr E, Glantschnig H, Wesolowski GA, et al. Osteoclast formation, survival and morphology are highly dependent on exogenous cholesterol/lipoproteins. Cell Death Differ,2004,11(suppl 1):S108-S118.
  • 4Vogelvang TE, van der Mooren MJ, Mijatovic V. Hormone replacement therapy, selective estrogen receptor modulators,and tissue-specific compounds: cardiovascular effects and clinical implications. Treat Endocrinol, 2004, 3 : 105-115.
  • 5Long JR, Liu PY, Liu YJ, et al. APOE haplotypes influence bone mineral density in Caucasian males but not females. Calcif Tissue Int, 2004, 75:299-304.
  • 6Sahin G, Polat G, Bagis S, et al. Study of axial bone mineral density in postmenopausal women with diffuse idiopathic skeletal hyperostosis related to type 2 diabetes mellitus. J Womens Health (Larchmt), 2002, 11:801-804.
  • 7Tzaphlidou M, Kafantari H. Influence of nutritional factors on bone collagen fibrils in ovariectomized rats. Bone, 2000, 27:635-638.
  • 8钟润泉,潘刚明,邓伟民.股骨上端几何结构和骨密度与骨质疏松性髋部骨折的关系[J].中国组织工程研究与临床康复,2007,11(45):9091-9094. 被引量:14
  • 9张磊,李牧,祁磊,蔡中续,李玉华,孙元亮.晚期糖基化终末产物在糖尿病大鼠骨质疏松发病中的作用及胰岛素潜在的防护机制[J].山东大学学报(医学版),2007,45(11):1148-1152. 被引量:4
  • 10Sydney L. Bonnick.Osteoporosis in men and women[J].Clinical Cornerstone.2006(1)

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