异丙酚联合米非司酮用于无痛人工流产的临床观察

Clinical observation of propofol combined with mifepristone in painless induced abortion

目的观察异丙酚联合米非司酮用于无痛人工流产的临床效果。方法 120例进行无痛人工流产手术患者,随机分为临床组与对照组,各60例。临床组应用异丙酚联合米非司酮进行无痛人工流产,对照组应用异丙酚进行无痛人工流产手术。比较两组患者的手术时间、出血量、麻醉起效时间、麻醉用药量、镇痛效果以及术后并发症等情况。结果临床组的宫颈软化率、麻醉起效时间、诱导麻醉用量、总麻醉用量、并发症发生情况与对照组相比,差异具有统计学意义(P<0.05)。结论使用异丙酚联合米非司酮在无痛人工流产中具有较好的软化宫颈作用,能够有效缩短麻醉起效时间,减少麻醉用量,降低并发症发生率,具有较好的临床应用价值。

Objective To observe clinical effects by propofol combined with mifepristone in painless induced abortion. Methods A total of 120 patients in painless induced abortion were randomly divided into clinical group and control group, with 60 cases in each group. The clinical group received propofol combined with mifepristone in painless induced abortion, and the control group received propofol in painless induced abortion. Comparisons were made on operation time, bleeding volume, anesthesia onset time, anesthetics dosage, analgesic effect and postoperative complications between the two groups. Results The differences of cervical softening rate, anesthesia onset time, anesthesia induction dosage, total anesthetics dosage, and occurrence of complications between the clinical group and the control group had statistical significance（P〈0.05）. Conclusion Implement of propofol combined with mifepristone in painless induced abortion provides precisely effect for cervical softening, and this method can effectively shorten anesthesia onset time, and reduce anesthetics dosage and incidence of complications. It contains good value for clinical application.