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红细胞分布宽度与慢性阻塞性肺疾病并发心力衰竭的相关性 被引量:2

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摘要 目的研究红细胞宽度(RDW)与慢性阻塞性肺疾病(COPD)并发心力衰竭的相关性。方法收集COPD患者234例作为COPD组,同时选取174例年龄、性别匹配的健康体检者作为对照组。回顾性分析患者入院时年龄、性别等基本资料;检测血常规、氨基末端脑钠肽前体(NT-pro BNP)、血气分析等实验室指标;肺功能等辅助检查。再根据血浆NT-pro BNP检测结果将COPD患者分成心力衰竭组60例和无心力衰竭组174例。对各组RDW水平的变化情况及与相应指标间的关系进行统计分析。结果 COPD组RDW水平明显高于对照组〔(15.3±1.9)%vs(12.9±0.5)%,P<0.001〕,心力衰竭组RDW水平明显高于无心力衰竭组〔(17.2±1.7%)vs(14.7±1.4)%,P<0.001〕,心力衰竭组RDW水平与血浆NTpro BNP水平呈正相关(r=0.576,P<0.001),ROC曲线法确定临界值,当RDW>16.8%时,RDW检测COPD并发心衰的敏感性为70%,特异性为91.3%。结论 RDW与COPD并发心力衰竭相关,可以作为COPD并发心力衰竭的一个早期检测指标。
作者 杨兆玲
出处 《中国老年学杂志》 CAS CSCD 北大核心 2016年第3期646-648,共3页 Chinese Journal of Gerontology
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