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老年白血病院内感染临床分析及防治 被引量:10

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摘要 目的探讨老年急性白血病(AL)患者院内感染特点及防治措施。方法收集86例老年AL患者临床资料,对其医院感染发生率、感染部位、致病菌和易感因素等进行回顾性分析,总结其院内感染特点。结果 86例中65例(75.6%)发生院内感染,最易发生院内感染的部位是呼吸系统50.8%(33/65),主要病原菌为G-杆菌。老年AL院内感染跟发病年龄、住院天数、外周血中性粒细胞计数(ANC)、骨髓增生程度、血红蛋白及血小板值、化疗缓解情况、粒系集落刺激因子(G-CSF)及抗生素使用情况、既往慢性病史有关。结论老年AL患者院内感染发生率高,对老年AL患者应制定个性化化疗方案,适当降低化疗药物剂量,加强保护性消毒隔离工作,严格把握使用抗生素的指征,联用G-CSF,适当缩短住院时间,加强输血对症支持治疗,可减少老年AL患者院内感染的发生率,降低其死亡率。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2016年第3期702-703,共2页 Chinese Journal of Gerontology
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