双源CT Flash模式双低剂量扫描联合SAFIRE在冠状动脉成像中的可行性研究

The Feasibility Study of Both Double Low Dose and SAFIRE on Dual Source CT Coronary Angiography with Flash Scan Mode

目的探讨双源CT(DSCT)Flash模式低电压、低浓度碘对比剂联合正弦图确定迭代重组(SAFIRE)在冠状动脉成像中的可行性。方法 64例行冠状动脉CT血管成像(CCTA)检查的患者随机分为A组(n=32,100k V,350 mg I/ml)和B组(n=32,80 k V,270 mg I/ml),B组图像经SAFIRE重组后获得C组,A组和B(C)组均采用Flash模式扫描。由2名放射科医师对照分析3组图像质量及辐射剂量。结果 A组和B(C)组患者的年龄、体质量指数(BMI)、平均心率比较差异无统计学意义(P>0.05),B(C)组的容积剂量指数(CTDIvol)、有效剂量长度乘积(DLP)和有效剂量(ED)明显低于A组(P<0.05)。A组和C组冠状动脉节段图像质量评分、噪声(SD)、信噪比(SNR)和对比噪声比(CNR)比较差异无统计学意义(P>0.05),但A组和B组、B组和C组间比较差异有统计学意义(P<0.05)。结论 CCTA在Flash模式下,低电压、低浓度碘对比剂联合SAFIRE技术的图像质量能满足诊断要求,而且能显著降低患者辐射剂量和不良反应发生。

Objective To investigate the feasibility of both low tube voltage and low concentrations of iodine contrast a- gent combined with SAFIRE on Dual Source CT coronary angiography in Flash scan mode. Methods 64 patients underg- one entire CT and CT coronary angiography （CCTA）were randomly divided into group A （n = 32,100 kV, 350 mgI/ml, FBP） and group B （n = 32,80 kV ,270 mgI/ml, FBP） , the images of group B were reconstructed with SAFIRE and taken as group C. Retrospectively,the quality of the image and the radiation dose of three groups were compared by two reviewers. Results Age, BMI, average heart rate of group A and group B were not statistically significant （P 〉 0.05 ）. CTDIvol, DLP and ED of group B was lower than those of group A （P 〈 0.05 ）. There were not statistically significant in coronary segments image quality score, SD, SNR and CNR of group A and group C, but those of both group A and group B and group C and group B had statistically significant （P 〈 0.05）. Conclusion CCTA in Flash scan mode, image quality of low tube voltage and low concentrations of iodine contrast agent combined with SAFIRE can meet diagnostic requirement, and obviously reduce radiation dose and adverse reactions occur.