CT引导经皮穿刺活检术诊断孤立性肺结节

CT-guided percutaneous biopsy in diagnosis of solitary pulmonary nodule

目的探讨CT引导下经皮穿刺孤立性肺结节活检的诊断效能及并发症。方法回顾性分析我院经皮穿刺孤立性肺结节活检患者225例,分析患者年龄、性别、吸烟史及穿刺病理结果及并发症,计算经皮穿刺活检诊断孤立性肺结节的效能。结果 225例患者中,病理诊断恶性结节154例(154/225,68.44%),良性结节71例(71/225,31.56%)。经皮穿刺活检诊断恶性孤立性肺结节的敏感度、特异度、准确率分别为99.33%(149/150)、93.33%(70/75)、97.33%(219/225)。术后气胸、咯血及肺出血发生率分别为15.11%(34/225)、5.33%(12/225)、9.33%(21/225),经对症处理后均消失。结论 CT引导下经皮穿刺活检是早期诊断孤立性肺结节方便、快捷、安全、有效的方法。

Objective To explore the diagnostic efficiency and complications of CT-guided percutaneous biopsy in solitary pulmonary nodule （SPN）. Methods Two hundred and twenty-five SPN patients underwent CT-guided pereutaneous tran- sthoracic needle biopsy. Patient＇s age, gender, smoking habits, biopsy results and complications were analyzed, and the efficiency of CT-guided percutaneous biopsy in diagnosis of SPN were calculated. Results Of 225 SPN patients, malignant were 154 cases （154/225, 68.44%） and benign were 71 cases （71/225, 31.56%） by CT-guided percutaneous biopsy. The diagnostic accuracy, sensitivity, and specificity of CT-guided percutaneous biopsy were 99.33% （ 149/150 ） and 93.33% （ 70/ 75）, 97.33% （219/225）, respectively. The incidences of pneumothorax, hemoptysis and pulmonary hemorrhage were 15.11% （34/225）, 5.33%（12/225）, 9.33% （21/225）, respectively, which were disappeared after symptomatic treatment. Conclusion CT-guided percutaneous biopsy for SPN is a convenient, quick, safe and effective early diagnostic method.