胎儿生长受限危险因素及分娩时机的分析

Analysis of Risk Factors for Fetal Growth Restriction and Delivery Timing

目的：探讨胎儿生长受限的相关危险因素及终止妊娠时机。方法：对2013年1月-2014年11月在郑州大学第三附属医院分娩的173例FGR新生儿（FGR组）及180例正常体重新生儿（对照组）及其产妇病历资料进行回顾性分析。结果：胎儿生长受限的高危因素有：妊娠期高血压疾病（P=0.000,OR=20.440,95%CI 8.499~49.156）、羊水过少（P=0.000,OR=5.652,95%CI 2.195~14.555）、妊娠期糖尿病（P=0.018,OR=2.763,95%CI 1.192~6.400）和贫血（P=0.032,OR=1.708,95%CI 1.047~2.786）。孕周越大,新生儿体重越重,预后越好,差异均有统计学意义（P〈0.05）。结论：妊娠期高血压疾病、羊水过少、妊娠期糖尿病、贫血是胎儿生长受限的高危因素,加强孕期保健及监护,规范治疗产科并发症,适时终止妊娠是降低围产儿死亡率的主要措施。

Objective：To explore the related risk factors for fetal growth restriction and time to termination of pregnancy. Method：The clinical data of 173 neonates with FGR（FGR group）,180 neonates with normal weight（normal group） and the parturient women in the Third Affiliated Hospital of Zhengzhou University were selected from January 2013 to November 2014,they were analyzed retrospectively. Result：The high risk factors of fetal growth restriction were： gestational hypertension disease（P=0.000,OR=20.440,95%CI 8.499-49.156）,oligohydramnios（P=0.000,OR=5.652,95%CI 2.195-14.555）,gestational diabetes（P=0.018,OR=2.763,95%CI 1.192-6.400） and anemia（P=0.032,OR=1.708,95%CI 1.047-2.786）.With the gestational age greater, the weight of the newborn was higher, the prognosis was better,the differences were statistically significant（P0.05）.Conclusion：Gestational hypertensiondisease, oligohydramnios, gestational diabetes and anemia are high risk factors of fetal growth restriction.To strengthen pregnancy care and custody,the standard treatment of obstetric complications, timely termination of pregnancy is main measures to reduce perinatal mortality.