降钙素原(PCT)预测菌血症的临床价值

The Clinical Value of Procalcitonin(PCT) to Predict Bacteremia

目的:探讨降钙素原(PCT)预测菌血症的临床价值。方法:选取本院2013年2月-2015年2月期间确诊为菌血症的110例患者,依据检测结果将其分为菌血症组60例和非菌血症组50例。记录所有患者首次血培养采集时的PCT结果、中性粒细胞绝对值(NEU)和白细胞计数(WBC),应用受试者工作特性曲线(ROC)评估各个炎性指标预测菌血症的临床价值。结果:菌血症组的NEU、WBC和PCT水平高于非菌血症组,且PCT的ROC曲线面积大于NEU、WBC,差异均有统计学意义(P<0.05),PCT临界值是0.43 ng/m L时可基本排除菌血症。结论:相较于NEU与WBC,PCT对菌血症的预测价值更高。

Objective：To investigate the clinical value of procalcitonin（PCT） to predict bacteremia. Method： 110 bacteremia patients in our hospital were selected from February 2013 to February 2015,they were divided into bacteremia group of 60 cases and non bacteremia group of 50 cases.The PCT results, the absolute value（NEU） and the white blood cell count（WBC） were recorded in all patients first blood culture collection.The bacteremia assessment clinical value of each inflammatory index was predicted by the receiver operating characteristic curve（ROC）. Result： The level of NEU, WBC and PCT of bacteremia group was higher than that of non bacteremia group, and, ROC curve area of PCT is greater than that of NEU and WBC, the differences were statistically significant（P0.05）.The critical PCT value was 0.43 ng/m L when basic rule out bacteremia.Conclusion：Compared with NEU and WBC, PCT of the higher predictive value of bacteremia.