胃癌根治切除联合胆囊切除的可行性研究

One stage cholecystectomy during radical gastrectomy for gastric cancer with gallbladder disease

目的分析胃癌合并胆囊疾病患者一期完成胃癌根治切除和胆囊切除术的可行性。方法回顾性分析2009年10月至2014年9月问天津医科大学总医院收治的702例胃癌患者临床病理资料，其中614例为胃癌患者行单纯根治切除术，88例为胃癌合并胆囊疾病患者一期行胃癌根治性切除和胆囊切除。结果胃癌根治切除联合胆囊切除组的平均手术时间为（348±111）min，比单纯胃癌切除组的手术时间（274±89）min延长（t=3．812，P〈0．05）。两组患者的术中失血量、平均住院天数、平均住院费用及术后并发症的发生率相比差异均无统计学意义（均P〉0．05）。联合切除术组的5年生存率为45．8％，单纯胃癌根治术组的5年生存率为49．0％．两组相比差异无统计学意义（χ2=0．646，P〉0．05）。结论对合并有胆囊疾病的胃癌患者行胃癌根治术同时实施胆囊切除是完全可行的。

Objective To evaluate radical gastrectomy combined with cholecystectomy for gastric cancer patients with concomitant gallbladder disease. Methods Clinical data of 702 gastric cancer patients undergoing radical gastrectomy （614 patients ） only or combined with cholecystectomy during radical gastrectomy from October 2009 to September 2014 in our department was retrospectively analyzed. Results The operating time of patients with simultaneous cholecystectomy was（ 348 ± 111 ）rain. the operating time of patients with radical gastrectomy only was （ 274 ± 89 ） min （ t = 3. 812, P 〈 0. 05 ）. Perioperative and postoperative complications, hospitalization expenses and 5-year survival rates were not statistically significant （ P 〉 0. 05 ）. Conclusions Radical gastrectomy with cholecystectomy for gastric cancer with gallbladder disease patients is safe and feasible.