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阵发性睡眠性血红蛋白尿11年后发生慢性粒细胞白血病1例报告

Paroxysmal nocturnal hemoglobinuria transforming to chronic myeloid leukemia: a case report
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摘要 1病历资料 患者男，63岁，2002年因“间断性茶色尿3个月”为主诉收入院。血常规：白细胞（WBC）3．8×10^9L，血红蛋白（Hh）72g／L，血小板（PLT）21×10^9／L，网织红细胞（Ret）0．6％。骨髓形态学：骨髓增生活跃，红系增生减低（10％）。Coombs试验阴性，Ham试验阳性，蔗糖溶血试验阳性，尿Rous试验阳性。
作者 陈月 陶善东 宋立孝 丁邦和 于亮
机构地区 南京医科大学附属淮安第一医院血液科
出处 《中国实用内科杂志》 CAS CSCD 北大核心 2016年第1期82-83,共2页 Chinese Journal of Practical Internal Medicine
基金 国家自然科学基金(81170489) 江苏省自然科学基金(BK20141254)
关键词 阵发性睡眠性血红蛋白尿 慢性粒细胞白血病 paroxysmal nocturnal hemoglobinuria chronic myeloid leukemia
分类号 R557.2 [医药卫生—血液循环系统疾病]
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参考文献11

  • 1Wang H, Chuhjo T, Yasue S, et al. Clinical significance of a minor population of paroxysmal nocturnal hemoglobinuria-type cells in bone marrow failure syndrome [J]. Blood, 2002, 100 (12): 3897-3902.
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  • 8Isoda A, Ogawa Y, Matsumoto M, et al. Coexistence of paroxysmal nocturnal hemoglobinuria (PNH) and acute lymphoblastic leukemia (ALL): is PNH a prodrome of ALL? [J]. Leuk Res, 2009, 33(3):e3-eS.
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二级参考文献15

  • 1齐静,彭晖,顾振纶,梁中琴,杨纯正.伊马替尼耐药的K562细胞系的建立及其生物学特性研究[J].中华血液学杂志,2004,25(6):337-341. 被引量：20
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中国实用内科杂志
2016年 第1期

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